Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:398
Official Symbol:ARHGDIG
Other Aliases:-
See related:HGNC:680|MIM:602844|HPRD:04163
Chromosome:16
Location:16p13.3
Gene Description:Rho GDP dissociation inhibitor (GDI) gamma
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0959
ORGANISM:human
Entrez Gene ID:398
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 2.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14570CBCerebellum100.089.4068489074707
14570CTXCerebral cortex100.076.6762237548828
14570HIPHippocampal region90.040203094482461.440315246582
14570HPFHippocampal formation95.817481994628971.3210601806641
14570HYHypothalamus81.669998168945353.6017608642578
14570LSXLateral septal complex29.967851638793914.9514741897583
14570MBMidbrain73.076526641845748.6691761016846
14570MYMedulla100.088.5874824523926
14570OLFOlfactory bulb100.084.8053665161133
14570PPons80.993591308593873.0123920440674
14570PALPallidum43.984669685363832.3152227401733
14570RHPRetrohippocampal region99.177177429199286.2533378601074
14570sAMYStriatum-like amygdalar nuclei70.953760147094753.0864925384521
14570STRStriatum37.428901672363323.3885674476624
14570STRdStriatum dorsal region30.446768760681219.4735426902771
14570STRvStriatum ventral region45.190212249755923.7778120040894
14570THThalamus57.210512161254935.0030431747437
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
398GO:0005094TASFunctionRho GDP-dissociation inhibitor activity
398GO:0005096IEAFunctionGTPase activator activity
398GO:0005737IEAComponentcytoplasm
398GO:0007162TASProcessnegative regulation of cell adhesion
398GO:0007266TASProcessRho protein signal transduction
398GO:0016023TASComponentcytoplasmic membrane-bound vesicle
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-998NP_001782.1cell division cycle 42 isoform 1HPRD00309
-5683NP_002778.1proteasome alpha 2 subunitHPRD08907
NP_001167.1998-CDC42HPRD04163
NP_001167.15879NP_942126.1ras-related C3 botulinum toxin substrate 1 isoform Rac1cBIND57832
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
398GDIT_HUMANQ99819IPR000406Rho_GDIRHO protein GDP dissociation inhibitor

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