Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:3987
Official Symbol:LIMS1
Other Aliases:PINCH|PINCH1
See related:HGNC:6616|MIM:602567|HPRD:03978
Chromosome:2
Location:2q12.3-q13
Gene Description:LIM and senescent cell antigen-like domains 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0416
ORGANISM:human
Entrez Gene ID:3987
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.5 :: 1.1 :: -1.2 :: -1.5 :: -1.4 :: -1.6
KARG Evidence 2
KARG ID:EVIM0484
ORGANISM:human
Entrez Gene ID:3987
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1 :: -1.2 :: -1.4 :: -2.1 :: -1.3
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
3987GO:0007569TASProcesscell aging
3987GO:0008270IEAFunctionzinc ion binding
3987GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004978.2--ILKBPHPRD03978
NP_004978.28440NP_003572.1NCK adaptor protein 2HPRD03978
NP_004978.28440NP_003572.1NCK adaptor protein 2HPRD05378
NP_004978.28440NP_003572.2NCK adaptor protein 2 isoform ABIND297461
NP_004978.255742NP_060692.1parvin, alphaHPRD16283
NP_004978.27114NP_066932.1thymosin, beta 4BIND185093
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
3987PINC_HUMANP48059IPR001781LIM_Zn_bdLIM, zinc-binding

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