Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:402
Official Symbol:ARL2
Other Aliases:ARFL2
See related:HGNC:693|MIM:601175|HPRD:11869
Chromosome:11
Location:11q13
Gene Description:ADP-ribosylation factor-like 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0189
ORGANISM:human
Entrez Gene ID:402
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15312160
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Upregulated
Fold Change:-
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
402GO:0000166IEAFunctionnucleotide binding
402GO:0005095TASFunctionGTPase inhibitor activity
402GO:0005525IEAFunctionGTP binding
402GO:0005622IEAComponentintracellular
402GO:0006364IEAProcessrRNA processing
402GO:0007021TASProcesstubulin folding
402GO:0007264IEAProcesssmall GTPase mediated signal transduction
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001658.16904-Tubulin specific chaperone DHPRD11869
NP_001658.123568-ADP ribosylation factor like 2 binding proteinHPRD11869
NP_001658.19094--BIND183968
NP_001658.15519-Protein phosphatase 2, structural/regulatory subunit A, betaHPRD11869
NP_001658.15521-Protein phosphatase 2, regulatory subunit B, betaHPRD11869
NP_001658.15522-Protein phosphatase 2A regulatory subunit B gamma isoformHPRD11869
NP_001658.15147NP_002592.1phosphodiesterase 6D, cGMP-specific, rod, deltaHPRD11869
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
402ARL2_HUMANP36404IPR006688ARFADP-ribosylation factor
402ARL2_HUMANP36404IPR006689ARF/SARARF/SAR superfamily
402ARL2_HUMANP36404IPR013753RasRas
402ARL2_HUMANP36404IPR001806Ras_trnsfrmngRas GTPase

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