Basic Information | Gene ID: | 4069 | Official Symbol: | LYZ | Other Aliases: | - | See related: | HGNC:6740|MIM:153450|HPRD:01085 | Chromosome: | 12 | Location: | 12q15 | Gene Description: | lysozyme (renal amyloidosis) | Gene type: | protein-coding | Gene Structure: |  | Genomic Context: |  |
KARG Evidence 1 | KARG ID: | EVIC0376 | ORGANISM: | human | Entrez Gene ID: | 4069 | Evidence Type: | Mapping from rat | Evidence ID Type: | Entrez Gene | Evidence ID: | 25211 | Addiction Drug: | | Addiction Drug Detail: | | Addiction Brain Area: | | Drug Effects: | | Fold Change: | |
KARG Evidence 2 | KARG ID: | EVIM0953 | ORGANISM: | human | Entrez Gene ID: | 4069 | Evidence Type: | Microarray | Evidence ID Type: | PUBMED | Evidence ID: | 11141048 | Addiction Drug: | ALCOHOL | Addiction Drug Detail: | ALCOHOL ABUSE | Addiction Brain Area: | Frontal Cortex | Drug Effects: | Downregulated | Fold Change: | -1.6 :: -2.5 |
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) | Mouse Entrez Gene ID | Brain Region | Brain Region Detail | Expression Level | Expression Density | 17105 | CB | Cerebellum | 1.9373379945755 | 6.02956247329712 | 77397 | CB | Cerebellum | 3.17286229133606 | 4.12975549697876 | 17110 | CB | Cerebellum | 7.62753760814667 | 12.964209318161 | 77397 | CTX | Cerebral cortex | 0.625334799289703 | 0.648368895053864 | 17105 | CTX | Cerebral cortex | 3.78402352333069 | 4.62433910369873 | 17110 | CTX | Cerebral cortex | 3.98969596624374 | 4.66230118274689 | 77397 | HIP | Hippocampal region | 0.50512957572937 | 0.463042616844177 | 17105 | HIP | Hippocampal region | 2.61221599578857 | 4.25836753845215 | 17110 | HIP | Hippocampal region | 3.84396761655807 | 5.56461822986603 | 77397 | HPF | Hippocampal formation | 0.397924661636353 | 0.441135913133621 | 17105 | HPF | Hippocampal formation | 3.21001291275024 | 6.63792896270752 | 17110 | HPF | Hippocampal formation | 3.75381934642792 | 4.99498927593231 | 77397 | HY | Hypothalamus | 0.155866518616676 | 0.391300231218338 | 17110 | HY | Hypothalamus | 2.15046334266663 | 2.87507212162018 | 17105 | HY | Hypothalamus | 2.49421620368958 | 3.9994490146637 | 77397 | LSX | Lateral septal complex | 0.137697219848633 | 0.397930771112442 | 17105 | LSX | Lateral septal complex | 2.05370903015137 | 2.97442150115967 | 17110 | LSX | Lateral septal complex | 2.8244594335556 | 3.85264670848846 | 77397 | MB | Midbrain | 0.848167419433594 | 1.93932235240936 | 17105 | MB | Midbrain | 2.2441737651825 | 6.09350919723511 | 17110 | MB | Midbrain | 4.18854916095734 | 6.90104126930237 | 77397 | MY | Medulla | 0.855095386505127 | 1.1059558391571 | 17105 | MY | Medulla | 1.59389972686768 | 3.8698251247406 | 17110 | MY | Medulla | 10.0730174779892 | 13.6633341312408 | 17105 | OLF | Olfactory bulb | 4.01399564743042 | 5.57634496688843 | 77397 | OLF | Olfactory bulb | 4.46913909912109 | 4.70082521438599 | 17110 | OLF | Olfactory bulb | 8.70047664642334 | 8.76270937919617 | 77397 | P | Pons | 0.320696175098419 | 0.615885078907013 | 17105 | P | Pons | 1.9606032371521 | 4.9012279510498 | 17110 | P | Pons | 5.36203789710999 | 7.89853858947754 | 77397 | PAL | Pallidum | 0.0511872693896294 | 0.0431036874651909 | 17105 | PAL | Pallidum | 1.98118162155151 | 2.8036413192749 | 17110 | PAL | Pallidum | 2.55664050579071 | 3.46492552757263 | 77397 | RHP | Retrohippocampal region | 0.194646582007408 | 0.327808022499084 | 17110 | RHP | Retrohippocampal region | 3.51807898283005 | 4.07770866155624 | 17105 | RHP | Retrohippocampal region | 3.87693071365356 | 8.86076259613037 | 77397 | sAMY | Striatum-like amygdalar nuclei | 0.0766932889819145 | 0.148567035794258 | 17110 | sAMY | Striatum-like amygdalar nuclei | 3.08793318271637 | 4.40932536125183 | 17105 | sAMY | Striatum-like amygdalar nuclei | 4.92880868911743 | 9.2091588973999 | 77397 | STR | Striatum | 0.232808902859688 | 0.283734381198883 | 17105 | STR | Striatum | 2.28635954856873 | 3.18385100364685 | 17110 | STR | Striatum | 3.04868042469025 | 3.61018073558807 | 77397 | STRd | Striatum dorsal region | 0.242318466305733 | 0.313184529542923 | 17105 | STRd | Striatum dorsal region | 2.19817495346069 | 3.05529069900513 | 17110 | STRd | Striatum dorsal region | 2.8193564414978 | 3.58940327167511 | 77397 | STRv | Striatum ventral region | 0.301034688949585 | 0.258616387844086 | 17105 | STRv | Striatum ventral region | 1.91396260261536 | 2.1446521282196 | 17110 | STRv | Striatum ventral region | 3.75853252410889 | 3.07889503240585 | 77397 | TH | Thalamus | 0.256241202354431 | 0.335321098566055 | 17105 | TH | Thalamus | 2.62004804611206 | 4.13396263122559 | 17110 | TH | Thalamus | 4.64548349380493 | 6.32116985321045 |
Gene Ontology | Gene ID | GO ID | Evidence | GO Type | GO Description | 4069 | GO:0003796 | IEA | Function | lysozyme activity | 4069 | GO:0005576 | IEA | Component | extracellular region | 4069 | GO:0005975 | IEA | Process | carbohydrate metabolism | 4069 | GO:0016798 | IEA | Function | hydrolase activity, acting on glycosyl bonds | 4069 | GO:0016998 | IEA | Process | cell wall catabolism | 4069 | GO:0019835 | IEA | Process | cytolysis | 4069 | GO:0042742 | IEA | Process | defense response to bacteria |
Interaction Information | Gene Product ID | Interactant Gene ID | Interactant Gene Product ID | Interactant Gene Product Name | Source | Source ID |
Domain Information | Gene ID | Uniprot/Swissprot ID | Uniprot/Swissprot ACC | Interpro ID | Interpro Short Description | Interpro Long Description | 4069 | LYSC_HUMAN | P61626 | IPR000974 | Glyco_hydro_22Ly | Glycoside hydrolase, family 22, lysozyme | 4069 | LYSC_HUMAN | P61626 | IPR001916 | Glyco_hydro_22 | Glycoside hydrolase, family 22 | 4069 | LYSC_HUMAN | P61626 | IPR000545 | Lactalbumin | Lactalbumin |
© Center for Bioinformatics(CBI), Peking University |
Any Comments and suggestions to : KARG GROUP. |
|