Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4070
Official Symbol:TACSTD2
Other Aliases:EGP-1|GA733|GA733-1|M1S1|TROP2
See related:HGNC:11530|MIM:137290|HPRD:00672
Chromosome:1
Location:1p32-p31
Gene Description:tumor-associated calcium signal transducer 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0376
ORGANISM:human
Entrez Gene ID:4070
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.3 :: -1.1 :: -1.6 :: -1.7 :: -1.6 :: -1.7
KARG Evidence 2
KARG ID:EVIM0444
ORGANISM:human
Entrez Gene ID:4070
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1.1 :: -1 :: -1.3 :: -3.2 :: -1.3
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
56753CBCerebellum28.79458427429242.7810249328613
56753CTXCerebral cortex28.854766845703122.3662090301514
56753HIPHippocampal region18.269729614257822.4548664093018
56753HPFHippocampal formation21.895948410034222.2597923278809
56753HYHypothalamus13.833609580993710.0979423522949
56753LSXLateral septal complex20.285259246826213.5989856719971
56753MBMidbrain18.837568283081117.3561172485352
56753MYMedulla18.827207565307620.2606678009033
56753OLFOlfactory bulb31.263305664062524.7117900848389
56753PPons18.845676422119118.6760234832764
56753PALPallidum11.70449829101569.26869487762451
56753RHPRetrohippocampal region28.032253265380922.4759254455566
56753sAMYStriatum-like amygdalar nuclei17.704071044921913.7062225341797
56753STRStriatum13.483057022094710.2031803131104
56753STRdStriatum dorsal region12.907664299011210.3673648834229
56753STRvStriatum ventral region10.93427944183357.09908246994019
56753THThalamus22.533622741699217.2988758087158
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4070GO:0004872TASFunctionreceptor activity
4070GO:0005829TASComponentcytosol
4070GO:0005887TASComponentintegral to plasma membrane
4070GO:0007166TASProcesscell surface receptor linked signal transduction
4070GO:0007601TASProcessvisual perception
4070GO:0008283TASProcesscell proliferation
4070GO:0016020TASComponentmembrane
4070GO:0050896IEAProcessresponse to stimulus
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
AAH09409.1-CAB46677.1polyproteinBIND195941
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4070TACD2_HUMANP09758IPR001231CD44_antigenCD44 antigen
4070TACD2_HUMANP09758IPR000716Thyroglobulin_1Thyroglobulin type-1

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.