Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4129
Official Symbol:MAOB
Other Aliases:MGC26382
See related:HGNC:6834|MIM:309860|HPRD:02401
Chromosome:X
Location:Xp11.23
Gene Description:monoamine oxidase B
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIL0082
ORGANISM:human
Entrez Gene ID:4129
Evidence Type:LT Reports
Evidence ID Type:PUBMED
Evidence ID:12563176
Addiction Drug:NICOTINE
Addiction Drug Detail:NICOTINE ABUSE
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIL0167
ORGANISM:human
Entrez Gene ID:4129
Evidence Type:LT Reports
Evidence ID Type:PUBMED
Evidence ID:15955630
Addiction Drug:NICOTINE
Addiction Drug Detail:NICOTINE ABUSE
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
109731CBCerebellum5.075564622879035.90200710296631
109731CTXCerebral cortex2.391326427459721.95348298549652
109731HIPHippocampal region1.260362207889561.03105852007866
109731HPFHippocampal formation2.604835033416752.16185301542282
109731HYHypothalamus2.952710509300233.99283277988434
109731LSXLateral septal complex2.271403849124912.33554410934448
109731MBMidbrain3.032006859779364.93010377883911
109731MYMedulla11.452359080314614.3960025310516
109731OLFOlfactory bulb2.876531839370732.10858708620071
109731PPons5.953286409378056.81744742393494
109731PALPallidum1.566679596900941.50699561834335
109731RHPRetrohippocampal region4.428366899490363.3272031545639
109731sAMYStriatum-like amygdalar nuclei2.214340567588811.53193964064121
109731STRStriatum5.332253336906434.66654634475708
109731STRdStriatum dorsal region5.646936655044565.12261629104614
109731STRvStriatum ventral region7.065688490867615.42250752449036
109731THThalamus18.286196708679220.9210977554321
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4129GO:0005740TASComponentmitochondrial envelope
4129GO:0006118IEAProcesselectron transport
4129GO:0008131IEAFunctionamine oxidase activity
4129GO:0016020IEAComponentmembrane
4129GO:0016021IEAComponentintegral to membrane
4129GO:0016491IEAFunctionoxidoreductase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000889.24129NP_000889.2monoamine oxidase BHPRD02401
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4129AOFB_HUMANP27338IPR000759Adrndx_reductaseAdrenodoxin reductase
4129AOFB_HUMANP27338IPR001613Amineoxid_flFlavin-containing amine oxidase
4129AOFB_HUMANP27338IPR002937Amino_oxidaseAmine oxidase
4129AOFB_HUMANP27338IPR000205NAD_BSNAD-binding site

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