Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4133
Official Symbol:MAP2
Other Aliases:DKFZp686I2148|MAP2A|MAP2B|MAP2C
See related:HGNC:6839|MIM:157130|HPRD:01140
Chromosome:2
Location:2q34-q35
Gene Description:microtubule-associated protein 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0594
ORGANISM:human
Entrez Gene ID:4133
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25595
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17756CBCerebellum100.0100.0
17756CTXCerebral cortex100.0100.0
17756HIPHippocampal region100.0100.0
17756HPFHippocampal formation100.0100.0
17756HYHypothalamus100.0100.0
17756LSXLateral septal complex100.0100.0
17756MBMidbrain100.0100.0
17756MYMedulla100.0100.0
17756OLFOlfactory bulb100.0100.0
17756PPons100.0100.0
17756PALPallidum100.0100.0
17756RHPRetrohippocampal region100.0100.0
17756sAMYStriatum-like amygdalar nuclei100.0100.0
17756STRStriatum100.0100.0
17756STRdStriatum dorsal region100.0100.0
17756STRvStriatum ventral region100.0100.0
17756THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4133GO:0000004NDProcessbiological process unknown
4133GO:0005198NASFunctionstructural molecule activity
4133GO:0005516IEAFunctioncalmodulin binding
4133GO:0005554NDFunctionmolecular function unknown
4133GO:0005856IEAComponentcytoskeleton
4133GO:0005874IEAComponentmicrotubule
4133GO:0005875NASComponentmicrotubule associated complex
4133GO:0005875TASComponentmicrotubule associated complex
4133GO:0007026IEAProcessnegative regulation of microtubule depolymerization
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-4647NP_000251.1myosin VIIAHPRD02043
-5339NP_958782.1plectin 1 isoform 6HPRD03180
NP_114034.1--cAMP dependent protein kinaseHPRD01140
NP_114034.1--ActinHPRD01140
NP_114034.15339-Plectin 1HPRD01140
NP_114034.14647-Myosin VIIAHPRD01140
NP_114034.164506-CPEB1HPRD01140
NP_114034.157787NP_113605.2MAP/microtubule affinity-regulating kinase 4HPRD09402
NP_114034.157787NP_113605.2MAP/microtubule affinity-regulating kinase 4HPRD01140
NP_114034.14133NP_114034.1microtubule-associated protein 2 isoform 3HPRD01140
NP_114034.184630NP_115927.1tau tubulin kinase 1HPRD11653
NP_114034.184630NP_115927.1tau tubulin kinase 1HPRD01140
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4133IPR013588MAP2_projctnMAP2/Tau projection
4133IPR001084Tau_tubulin_bdTubulin-binding Tau protein
4133MAP2_HUMANP11137IPR013588MAP2_projctnMAP2/Tau projection
4133MAP2_HUMANP11137IPR001084Tau_tubulin_bdTubulin-binding Tau protein

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