Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4197
Official Symbol:MDS1
Other Aliases:MDS1-EVI1|PRDM3
See related:HGNC:6979|MIM:600049
Chromosome:3
Location:3q26
Gene Description:myelodysplasia syndrome 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0252
ORGANISM:human
Entrez Gene ID:4197
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Upregulated
Fold Change:0.82
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17251CBCerebellum3.817189455032356.45319700241089
17251CTXCerebral cortex3.103331804275514.75386047363281
17251HIPHippocampal region2.115207195281983.45413708686829
17251HPFHippocampal formation1.664746403694152.30031085014343
17251HYHypothalamus0.1082582324743270.0851622968912125
17251LSXLateral septal complex0.09294395148754120.234896644949913
17251MBMidbrain1.80206012725832.57128810882568
17251MYMedulla4.495732307434084.71104192733765
17251OLFOlfactory bulb1.046765208244321.736652135849
17251PPons1.245861649513241.5084822177887
17251PALPallidum0.3103237748146060.28895691037178
17251RHPRetrohippocampal region0.8051947355270390.712549984455109
17251sAMYStriatum-like amygdalar nuclei0.1218991279602050.17074491083622
17251STRStriatum0.4288127422332760.918678224086761
17251STRdStriatum dorsal region0.6317194700241091.4502557516098
17251STRvStriatum ventral region0.1155520826578140.0776886716485023
17251THThalamus4.211345195770266.29676914215088
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4197GO:0003700TASFunctiontranscription factor activity
4197GO:0005524IEAFunctionATP binding
4197GO:0005634IEAComponentnucleus
4197GO:0006355IEAProcessregulation of transcription, DNA-dependent
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004982.151199NP_065972.2ninein isoform 2HPRD09785
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4197MDS1_HUMANQ13465

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