Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4287
Official Symbol:ATXN3
Other Aliases:AT3|ATX3|JOS|MJD|MJD1|SCA3
See related:HGNC:7106|MIM:607047|HPRD:06131
Gene Description:ataxin 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
Entrez Gene ID:4287
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:2.05 :: 1.79 :: 2.09 :: 1.41 :: -1.95 :: -1.95 :: -1.91
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4287GO:0006289TASProcessnucleotide-excision repair
4287GO:0006355IEAProcessregulation of transcription, DNA-dependent
4287GO:0007268TASProcesssynaptic transmission
4287GO:0007399TASProcessnervous system development
4287GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-5887NP_002865.1UV excision repair protein RAD23 homolog BHPRD06772
-5887NP_002865.1UV excision repair protein RAD23 homolog BBIND194704
-5886NP_005044.1UV excision repair protein RAD23 homolog AHPRD07191
-5886NP_005044.1UV excision repair protein RAD23 homolog ABIND194703
NP_004984.27415NP_009057.1valosin-containing proteinHPRD06131
NP_004984.27415NP_009057.1valosin-containing proteinHPRD03013
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4287IPR006155JosephinMachado-Joseph disease protein MJD
4287IPR003903UIMUbiquitin interacting motif

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