Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4336
Official Symbol:MOBP
Other Aliases:MGC87379
See related:HGNC:7189|MIM:600948|HPRD:02973
Chromosome:3
Location:3p22.1
Gene Description:myelin-associated oligodendrocyte basic protein
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0324
ORGANISM:human
Entrez Gene ID:4336
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:17433
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0071
ORGANISM:human
Entrez Gene ID:4336
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-1.85 :: -0.23 :: -0.24 :: -1.06 :: -1.61 :: -0.48 :: -1.11 :: -0.18 :: 0.21 :: -1.48
KARG Evidence 3
KARG ID:EVIM0381
ORGANISM:human
Entrez Gene ID:4336
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.1 :: 1.1 :: 2.8 :: 3.5 :: 1.7 :: 2.2
KARG Evidence 4
KARG ID:EVIM0449
ORGANISM:human
Entrez Gene ID:4336
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Upregulated
Fold Change:1.3 :: 1.2 :: 1.2 :: 2.8 :: 1.9
KARG Evidence 5
KARG ID:EVIM0815
ORGANISM:human
Entrez Gene ID:4336
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-2.1 :: -1.9 :: -1.7 :: -1.7
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17433CBCerebellum55.19106864929268.5915412902832
17433CTXCerebral cortex56.612884521484449.4294967651367
17433HIPHippocampal region53.856025695800862.0995559692383
17433HPFHippocampal formation56.776472091674858.9758205413818
17433HYHypothalamus87.442413330078178.2806205749512
17433LSXLateral septal complex91.365432739257884.6669387817383
17433MBMidbrain100.097.1470947265625
17433MYMedulla97.84844589233491.4262008666992
17433OLFOlfactory bulb57.183376312255954.5914611816406
17433PPons100.0100.0
17433PALPallidum100.097.9937477111816
17433RHPRetrohippocampal region60.450204849243253.5521697998047
17433sAMYStriatum-like amygdalar nuclei60.818347930908252.5176277160645
17433STRStriatum79.199188232421975.3835105895996
17433STRdStriatum dorsal region87.472221374511787.1867828369141
17433STRvStriatum ventral region57.470300674438548.8368015289307
17433THThalamus100.093.5637245178223
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4336GO:0005625TASComponentsoluble fraction
4336GO:0007399TASProcessnervous system development
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4336IPR000637AT_hook_DNA_bdHMG-I and HMG-Y, DNA-binding
4336IPR005819Histone_H5Histone H5
4336IPR006788MOBPMyelin-associated oligodendrocytic basic protein (MOBP)
4336IPR000694PRO_richProline-rich region

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