Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4512
Official Symbol:COX1
Other Aliases:MTCO1
See related:HGNC:7419
Chromosome:MT
Location:-
Gene Description:cytochrome c oxidase subunit I
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0195
ORGANISM:human
Entrez Gene ID:4512
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:17708
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC0383
ORGANISM:human
Entrez Gene ID:4512
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:26195
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4512GO:0004129NASFunctioncytochrome-c oxidase activity
4512GO:0005506IEAFunctioniron ion binding
4512GO:0005507IEAFunctioncopper ion binding
4512GO:0005739IEAComponentmitochondrion
4512GO:0005746IEAComponentmitochondrial electron transport chain
4512GO:0006118IEAProcesselectron transport
4512GO:0006123NASProcessmitochondrial electron transport, cytochrome c to oxygen
4512GO:0016020IEAComponentmembrane
4512GO:0016021IEAComponentintegral to membrane
4512GO:0016491IEAFunctionoxidoreductase activity
4512GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
AAK17573.1--COX4HPRD02469
AAK17573.19377NP_004246.1cytochrome c oxidase subunit Va precursorHPRD04799
AAK17573.19377NP_004246.1cytochrome c oxidase subunit Va precursorHPRD02469
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4512COX1_HUMANP00395IPR000883COX1Cytochrome c oxidase, subunit I

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