Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4632
Official Symbol:MYL1
Other Aliases:MLC1F|MLC3F
See related:HGNC:7582|MIM:160780|HPRD:01180
Chromosome:2
Location:2q33-q34
Gene Description:myosin, light polypeptide 1, alkali; skeletal, fast
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0471
ORGANISM:human
Entrez Gene ID:4632
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:56781
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17901CBCerebellum35.993186950683657.5690841674805
17901CTXCerebral cortex68.492942810058657.8138542175293
17901HIPHippocampal region27.377243041992240.4933319091797
17901HPFHippocampal formation28.805673599243234.6688919067383
17901HYHypothalamus7.556116580963135.54547023773193
17901LSXLateral septal complex10.63834285736086.81299257278442
17901MBMidbrain9.63120841979988.54106616973877
17901MYMedulla13.91274547576915.2830190658569
17901OLFOlfactory bulb45.366111755371139.0327072143555
17901PPons7.393306732177737.50559759140015
17901PALPallidum10.21191024780278.12212181091309
17901RHPRetrohippocampal region31.548727035522527.1714038848877
17901sAMYStriatum-like amygdalar nuclei16.139516830444310.5357608795166
17901STRStriatum27.59444618225120.6543579101562
17901STRdStriatum dorsal region32.342502593994125.2117080688477
17901STRvStriatum ventral region23.46976280212415.524956703186
17901THThalamus12.119636535644512.8070421218872
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4632GO:0003774IEAFunctionmotor activity
4632GO:0005509IEAFunctioncalcium ion binding
4632GO:0005859NASComponentmuscle myosin
4632GO:0007517NASProcessmuscle development
4632GO:0008307NASFunctionstructural constituent of muscle
4632GO:0016459IEAComponentmyosin
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4632MLE1_HUMANP05976IPR013567EF_hand_assoc_2EF hand associated, type-2
4632MLE1_HUMANP05976IPR002048EF_hand_Ca_bdCalcium-binding EF-hand
4632MLE1_HUMANP05976IPR013684Miro-likeMiro-like
4632MLE1_HUMANP05976IPR013623NADPH_OxNADPH oxidase Respiratory burst
4632MLE3_HUMANP06741IPR013567EF_hand_assoc_2EF hand associated, type-2
4632MLE3_HUMANP06741IPR002048EF_hand_Ca_bdCalcium-binding EF-hand
4632MLE3_HUMANP06741IPR013684Miro-likeMiro-like
4632MLE3_HUMANP06741IPR013623NADPH_OxNADPH oxidase Respiratory burst

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