Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4661
Official Symbol:MYT1
Other Aliases:C20orf36|MTF1|MYTI|PLPB1
See related:HGNC:7622|MIM:600379|HPRD:02659
Chromosome:20
Location:20q13.33
Gene Description:myelin transcription factor 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0837
ORGANISM:human
Entrez Gene ID:4661
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:1.1 :: 1.2 :: -1.2 :: -1.8
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
17932CBCerebellum89.5760231018066100.0
17932CTXCerebral cortex30.412614822387719.8990125656128
17932HIPHippocampal region59.185024261474678.4690322875977
17932HPFHippocampal formation46.645574569702151.3210029602051
17932HYHypothalamus59.81289482116744.249755859375
17932LSXLateral septal complex100.0100.0
17932MBMidbrain48.583318710327138.3914775848389
17932MYMedulla51.707172393798848.6337089538574
17932OLFOlfactory bulb73.87329101562564.8525772094727
17932PPons43.810390472412136.0135326385498
17932PALPallidum42.618515014648432.3152341842651
17932RHPRetrohippocampal region29.710778236389221.1600160598755
17932sAMYStriatum-like amygdalar nuclei56.103223800659238.0990686416626
17932STRStriatum40.905713081359931.2436513900757
17932STRdStriatum dorsal region25.255645751953118.4711503982544
17932STRvStriatum ventral region44.231176376342830.5101318359375
17932THThalamus92.446937561035281.8621444702148
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4661GO:0003700IEAFunctiontranscription factor activity
4661GO:0003700NASFunctiontranscription factor activity
4661GO:0005515IPIFunctionprotein binding
4661GO:0005634IEAComponentnucleus
4661GO:0005634NASComponentnucleus
4661GO:0006350IEAProcesstranscription
4661GO:0006355IEAProcessregulation of transcription, DNA-dependent
4661GO:0006355NASProcessregulation of transcription, DNA-dependent
4661GO:0007399IEAProcessnervous system development
4661GO:0008270IEAFunctionzinc ion binding
4661GO:0008270NASFunctionzinc ion binding
4661GO:0030154IEAProcesscell differentiation
4661GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004526.15300NP_006212.1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1BIND151902
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4661MYT1_HUMANQ01538IPR013681Myelin_TFMyelin transcription factor 1
4661MYT1_HUMANQ01538IPR002515Znf_C2HCZinc finger, C2HC-type

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