Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4671
Official Symbol:BIRC1
Other Aliases:NAIP|psiNAIP
See related:HGNC:7634|MIM:600355
Chromosome:5
Location:5q13.1
Gene Description:baculoviral IAP repeat-containing 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0218
ORGANISM:human
Entrez Gene ID:4671
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Upregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4671GO:0000166IEAFunctionnucleotide binding
4671GO:0005524IEAFunctionATP binding
4671GO:0005622IEAComponentintracellular
4671GO:0006915IEAProcessapoptosis
4671GO:0006916IEAProcessanti-apoptosis
4671GO:0006916TASProcessanti-apoptosis
4671GO:0007399TASProcessnervous system development
4671GO:0017111IEAFunctionnucleoside-triphosphatase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004527.158484NP_067032.3caspase recruitment domain protein 12BIND216606
NP_004527.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4671BIRC1_HUMANQ13075IPR000767Disease_resistDisease resistance protein
4671BIRC1_HUMANQ13075IPR007111NACHT_NTPaseNACHT nucleoside triphosphatase
4671BIRC1_HUMANQ13075IPR001370Prot_inh_I32_IAPProteinase inhibitor I32, inhibitor of apoptosis

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