Knowledgebase for Addiction-Related Genes
KARG (Knowledgebase for Addiction Related
>> Gene Entry
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.
Basic Information Gene ID: 4763 Official Symbol: NF1 Other Aliases: DKFZp686J1293|NFNS|VRNF|WSS See related: HGNC:7765|MIM:162200|HPRD:01203 Chromosome: 17 Location: 17q11.2 Gene Description: neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) Gene type: protein-coding Gene Structure: Genomic Context:
KARG Evidence 1 KARG ID: EVIC0424 ORGANISM: human Entrez Gene ID: 4763 Evidence Type: Mapping from rat Evidence ID Type: Entrez Gene Evidence ID: 24592 Addiction Drug: Addiction Drug Detail: Addiction Brain Area: Drug Effects: Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density
Gene Ontology Gene ID GO ID Evidence GO Type GO Description 4763 GO:0000004 ND Process biological process unknown 4763 GO:0004857 TAS Function enzyme inhibitor activity 4763 GO:0005099 NR Function Ras GTPase activator activity 4763 GO:0005554 ND Function molecular function unknown 4763 GO:0005737 TAS Component cytoplasm 4763 GO:0007049 IEA Process cell cycle 4763 GO:0007265 NR Process Ras protein signal transduction 4763 GO:0008285 TAS Process negative regulation of cell proliferation 4763 GO:0008372 ND Component cellular component unknown 4763 GO:0045786 IEA Process negative regulation of progression through cell cycle
Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 7266 AAH11837.2 DNAJC7 protein HPRD 07046 AAA59925.1 7266 - DnaJ homolog subfamily C member 7 HPRD 01203
Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 4763 IPR001251 CRAL_bd_TRIO_C Cellular retinaldehyde-binding/triple function, C-terminal 4763 IPR001936 RasGAP Ras GTPase-activating protein
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