Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4763
Official Symbol:NF1
Other Aliases:DKFZp686J1293|NFNS|VRNF|WSS
See related:HGNC:7765|MIM:162200|HPRD:01203
Chromosome:17
Location:17q11.2
Gene Description:neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0424
ORGANISM:human
Entrez Gene ID:4763
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24592
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4763GO:0000004NDProcessbiological process unknown
4763GO:0004857TASFunctionenzyme inhibitor activity
4763GO:0005099NRFunctionRas GTPase activator activity
4763GO:0005554NDFunctionmolecular function unknown
4763GO:0005737TASComponentcytoplasm
4763GO:0007049IEAProcesscell cycle
4763GO:0007265NRProcessRas protein signal transduction
4763GO:0008285TASProcessnegative regulation of cell proliferation
4763GO:0008372NDComponentcellular component unknown
4763GO:0045786IEAProcessnegative regulation of progression through cell cycle
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7266AAH11837.2DNAJC7 proteinHPRD07046
AAA59925.17266-DnaJ homolog subfamily C member 7HPRD01203
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4763IPR001251CRAL_bd_TRIO_CCellular retinaldehyde-binding/triple function, C-terminal
4763IPR001936RasGAPRas GTPase-activating protein

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