Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4774
Official Symbol:NFIA
Other Aliases:DKFZp434L0422|KIAA1439|NFI-L
See related:HGNC:7784|MIM:600727|HPRD:09007
Chromosome:1
Location:1p31.3-p31.2
Gene Description:nuclear factor I/A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0432
ORGANISM:human
Entrez Gene ID:4774
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25492
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0236
ORGANISM:human
Entrez Gene ID:4774
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Upregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18027CBCerebellum35.098467826843320.4576649665833
18027CTXCerebral cortex7.474099159240724.72521889209747
18027HIPHippocampal region35.129267692565934.8024320602417
18027HPFHippocampal formation24.272428512573221.3554239273071
18027HYHypothalamus1.589104235172271.09311720728874
18027LSXLateral septal complex11.75204992294319.52501678466797
18027MBMidbrain2.297453880310061.81876230239868
18027MYMedulla5.291687011718754.78347396850586
18027OLFOlfactory bulb24.002930641174314.9778561592102
18027PPons3.689708948135384.10166442394257
18027PALPallidum0.9806407988071440.761114031076431
18027RHPRetrohippocampal region6.531373023986824.29619133472443
18027sAMYStriatum-like amygdalar nuclei3.485900521278382.06229853630066
18027STRStriatum4.564580798149114.27505600452423
18027STRdStriatum dorsal region3.126064538955693.48690783977509
18027STRvStriatum ventral region4.004528999328612.64501762390137
18027THThalamus2.343316137790681.62840515375137
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4774GO:0003700IEAFunctiontranscription factor activity
4774GO:0003700NASFunctiontranscription factor activity
4774GO:0005634IEAComponentnucleus
4774GO:0005634NASComponentnucleus
4774GO:0006118IEAProcesselectron transport
4774GO:0006260IEAProcessDNA replication
4774GO:0006350IEAProcesstranscription
4774GO:0006355IEAProcessregulation of transcription, DNA-dependent
4774GO:0006355NASProcessregulation of transcription, DNA-dependent
4774GO:0019079NASProcessviral genome replication
4774GO:0020037IEAFunctionheme binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4774IPR000647CTF_NFICTF/NF-I
4774IPR003619Dwarfin_ADwarfin protein, A
4774IPR000694PRO_richProline-rich region

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