Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:478
Official Symbol:ATP1A3
Other Aliases:DYT12|MGC13276|RDP
See related:HGNC:801|MIM:182350|HPRD:01666
Chromosome:19
Location:19q13.31
Gene Description:ATPase, Na+/K+ transporting, alpha 3 polypeptide
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0370
ORGANISM:human
Entrez Gene ID:478
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24213
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
232975CBCerebellum94.353443145752100.0
232975CTXCerebral cortex100.0100.0
232975HIPHippocampal region100.0100.0
232975HPFHippocampal formation100.0100.0
232975HYHypothalamus100.0100.0
232975LSXLateral septal complex100.0100.0
232975MBMidbrain100.0100.0
232975MYMedulla100.0100.0
232975OLFOlfactory bulb100.0100.0
232975PPons100.0100.0
232975PALPallidum100.0100.0
232975RHPRetrohippocampal region100.0100.0
232975sAMYStriatum-like amygdalar nuclei100.0100.0
232975STRStriatum100.0100.0
232975STRdStriatum dorsal region100.0100.0
232975STRvStriatum ventral region100.0100.0
232975THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
478GO:0000166IEAFunctionnucleotide binding
478GO:0000287IEAFunctionmagnesium ion binding
478GO:0005391ISSFunctionsodium:potassium-exchanging ATPase activity
478GO:0005524IEAFunctionATP binding
478GO:0005890ISSComponentsodium:potassium-exchanging ATPase complex
478GO:0006813ISSProcesspotassium ion transport
478GO:0006814ISSProcesssodium ion transport
478GO:0008152IEAProcessmetabolism
478GO:0015077IEAFunctionmonovalent inorganic cation transporter activity
478GO:0015991ISSProcessATP hydrolysis coupled proton transport
478GO:0016020IEAComponentmembrane
478GO:0016787IEAFunctionhydrolase activity
478GO:0016820IEAFunctionhydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
478GO:0030317ISSProcesssperm motility
478GO:0030641ISSProcesshydrogen ion homeostasis
478GO:0030955IEAFunctionpotassium ion binding
478GO:0031402IEAFunctionsodium ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
478AT1A3_HUMANP13637IPR006069ATPase_cat_aATPase, P-type cation exchange, alpha subunit
478AT1A3_HUMANP13637IPR001757ATPase_PATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
478AT1A3_HUMANP13637IPR004014ATPase_P_cat_NATPase, P-type cation-transporter, N-terminal
478AT1A3_HUMANP13637IPR006068ATPase_P_cat_CATPase, P-type cation-transporter, C-terminal
478AT1A3_HUMANP13637IPR005834Dehal_like_hydroHaloacid dehalogenase-like hydrolase
478AT1A3_HUMANP13637IPR008250E1-E2_ATPase_regE1-E2 ATPase-associated region
478AT1A3_HUMANP13637IPR000695H_ATPaseH+ transporting ATPase, proton pump

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