Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4799
Official Symbol:NFX1
Other Aliases:MGC20369|NFX2
See related:HGNC:7803|MIM:603255|HPRD:11936
Chromosome:9
Location:9p13.3
Gene Description:nuclear transcription factor, X-box binding 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0877
ORGANISM:human
Entrez Gene ID:4799
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
74164CBCerebellum39.709941864013743.345516204834
74164CTXCerebral cortex100.081.4794845581055
74164HIPHippocampal region73.7963638305664100.0
74164HPFHippocampal formation89.2950897216797100.0
74164HYHypothalamus88.149986267089870.2687683105469
74164LSXLateral septal complex80.4086914062561.0466957092285
74164MBMidbrain74.147201538085964.2926940917969
74164MYMedulla71.275970458984480.3510589599609
74164OLFOlfactory bulb83.686302185058675.5210189819336
74164PPons66.174018859863371.1470108032227
74164PALPallidum74.468116760253965.9937896728516
74164RHPRetrohippocampal region100.0100.0
74164sAMYStriatum-like amygdalar nuclei100.094.5069961547852
74164STRStriatum100.0100.0
74164STRdStriatum dorsal region100.0100.0
74164STRvStriatum ventral region100.0100.0
74164THThalamus90.266838073730576.1113433837891
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4799GO:0000122TASProcessnegative regulation of transcription from RNA polymerase II promoter
4799GO:0003676IEAFunctionnucleic acid binding
4799GO:0003700IEAFunctiontranscription factor activity
4799GO:0003700TASFunctiontranscription factor activity
4799GO:0005515IEAFunctionprotein binding
4799GO:0005634IEAComponentnucleus
4799GO:0006350IEAProcesstranscription
4799GO:0006355IEAProcessregulation of transcription, DNA-dependent
4799GO:0006366TASProcesstranscription from RNA polymerase II promoter
4799GO:0006397IEAProcessmRNA processing
4799GO:0006406IEAProcessmRNA export from nucleus
4799GO:0006512IEAProcessubiquitin cycle
4799GO:0006810IEAProcesstransport
4799GO:0006954TASProcessinflammatory response
4799GO:0008270IEAFunctionzinc ion binding
4799GO:0016874IEAFunctionligase activity
4799GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4799IPR001374R3H_ss_bdSingle-stranded nucleic acid binding R3H
4799IPR000967Znf_NFX1Zinc finger, NF-X1-type
4799IPR001965Znf_PHDZinc finger, PHD-type
4799IPR001841Znf_RINGZinc finger, RING-type

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