Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4821
Official Symbol:NKX2-2
Other Aliases:NKX2.2|NKX2B
See related:HGNC:7835|MIM:604612|HPRD:05213
Chromosome:20
Location:20pter-q11.23
Gene Description:NK2 transcription factor related, locus 2 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0359
ORGANISM:human
Entrez Gene ID:4821
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18088
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18088CBCerebellum16.648294448852519.2061367034912
18088CTXCerebral cortex20.602437973022514.6075420379639
18088HIPHippocampal region16.262460708618217.9588050842285
18088HPFHippocampal formation15.447652816772514.5683259963989
18088HYHypothalamus5.747269630432134.35317897796631
18088LSXLateral septal complex8.56445884704595.80850315093994
18088MBMidbrain6.805827617645266.11322975158691
18088MYMedulla11.243320465087910.8579654693604
18088OLFOlfactory bulb23.831733703613317.8212146759033
18088PPons8.218795776367197.87065029144287
18088PALPallidum4.660004138946533.58422803878784
18088RHPRetrohippocampal region13.33259582519539.2443208694458
18088sAMYStriatum-like amygdalar nuclei11.43115329742437.99118137359619
18088STRStriatum11.74153995513928.17588806152344
18088STRdStriatum dorsal region13.42332363128669.66704845428467
18088STRvStriatum ventral region7.924296379089364.87546491622925
18088THThalamus13.392253875732410.751181602478
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4821GO:0003700IEAFunctiontranscription factor activity
4821GO:0005634IEAComponentnucleus
4821GO:0006355IEAProcessregulation of transcription, DNA-dependent
4821GO:0007275IEAProcessdevelopment
4821GO:0007420TASProcessbrain development
4821GO:0043565IEAFunctionsequence-specific DNA binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4821NKX22_HUMANO95096IPR001356HomeoboxHomeobox
4821NKX22_HUMANO95096IPR000327POUPOU

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.