Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4884
Official Symbol:NPTX1
Other Aliases:DKFZp686J2446|MGC105123|NP1
See related:HGNC:7952|MIM:602367|HPRD:03843
Chromosome:17
Location:17q25.1-q25.2
Gene Description:neuronal pentraxin I
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0172
ORGANISM:human
Entrez Gene ID:4884
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18164
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0187
ORGANISM:human
Entrez Gene ID:4884
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18164CBCerebellum50.0066680908203100.0
18164CTXCerebral cortex99.6957092285156100.0
18164HIPHippocampal region100.0100.0
18164HPFHippocampal formation90.2036666870117100.0
18164HYHypothalamus19.341089248657219.0227293968201
18164LSXLateral septal complex35.876588821411136.6391792297363
18164MBMidbrain28.527570724487330.2237720489502
18164MYMedulla35.383783340454146.2721118927002
18164OLFOlfactory bulb74.874797821044997.9448089599609
18164PPons16.93519735336319.4654812812805
18164PALPallidum14.933967113494913.903466463089
18164RHPRetrohippocampal region59.174547195434670.2337684631348
18164sAMYStriatum-like amygdalar nuclei32.678403854370133.9268131256104
18164STRStriatum13.584220170974713.8470115661621
18164STRdStriatum dorsal region6.237781763076786.44800317287445
18164STRvStriatum ventral region15.108471870422413.1811623573303
18164THThalamus10.094095230102512.3717875480652
KARG Evidence 3
KARG ID:QTL0187
Trait:chronic alcohol withdrawal severity
Peak:75
Peak Marker:D11Mit203
Parents:IP2 x IR1 F2
Evidence ID:12925894
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4884GO:0005509IEAFunctioncalcium ion binding
4884GO:0006810TASProcesstransport
4884GO:0007268TASProcesssynaptic transmission
4884GO:0007417TASProcesscentral nervous system development
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-23467NP_055108.2neuronal pentraxin receptor isoform 1HPRD14837
NP_002513.1--NPRHPRD03843
NP_002513.14884NP_002513.1neuronal pentraxin I precursorHPRD03843
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4884NPTX1_HUMANQ15818IPR001759PentaxinPentaxin

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