Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4885
Official Symbol:NPTX2
Other Aliases:NARP|NP-II|NP2
See related:HGNC:7953|MIM:600750|HPRD:02853
Chromosome:7
Location:7q21.3-q22.1
Gene Description:neuronal pentraxin II
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0222
ORGANISM:human
Entrez Gene ID:4885
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Upregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
53324CBCerebellum67.6484432220459100.0
53324CTXCerebral cortex73.479137420654374.4091510772705
53324HIPHippocampal region43.594418525695877.1940326690674
53324HPFHippocampal formation45.053485870361363.0376529693604
53324HYHypothalamus22.735770702362120.7522029876709
53324LSXLateral septal complex12.65671563148511.7322902679443
53324MBMidbrain29.923456192016627.3039979934692
53324MYMedulla26.01543521881125.5040483474731
53324OLFOlfactory bulb76.230518341064585.3418464660645
53324PPons18.009420871734617.6446325778961
53324PALPallidum21.114638090133718.5624811649323
53324RHPRetrohippocampal region48.669313430786145.7393598556519
53324sAMYStriatum-like amygdalar nuclei17.067380428314214.0512173175812
53324STRStriatum30.653372764587424.0470032691956
53324STRdStriatum dorsal region30.203193187713623.0621612071991
53324STRvStriatum ventral region44.016613960266133.3316254615784
53324THThalamus48.583184242248549.2593326568604
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4885GO:0005509IEAFunctioncalcium ion binding
4885GO:0005529IEAFunctionsugar binding
4885GO:0005554NDFunctionmolecular function unknown
4885GO:0007268NASProcesssynaptic transmission
4885GO:0008372NDComponentcellular component unknown
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002514.1--NPRHPRD02853
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4885NPTX2_HUMANP47972IPR001759PentaxinPentaxin

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