Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4897
Official Symbol:NRCAM
Other Aliases:KIAA0343
See related:HGNC:7994|MIM:601581|HPRD:07207
Chromosome:7
Location:7q31.1-q31.2
Gene Description:neuronal cell adhesion molecule
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIL0199
ORGANISM:human
Entrez Gene ID:4897
Evidence Type:LT Reports
Evidence ID Type:PUBMED
Evidence ID:16123759
Addiction Drug:POLYSUBSTANCE
Addiction Drug Detail:DRUG ABUSE
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
319504CBCerebellum24.490669250488333.1158199310303
319504CTXCerebral cortex96.29047012329192.386043548584
319504HIPHippocampal region71.1053123474121100.0
319504HPFHippocampal formation82.3699417114258100.0
319504HYHypothalamus13.616278171539311.083080291748
319504LSXLateral septal complex13.616063833236711.5549082756042
319504MBMidbrain12.670441150665312.4378952980042
319504MYMedulla21.801427841186532.9016132354736
319504OLFOlfactory bulb92.204921722412180.6957378387451
319504PPons16.662789344787619.6772561073303
319504PALPallidum13.526091098785413.1913621425629
319504RHPRetrohippocampal region97.608852386474694.0371627807617
319504sAMYStriatum-like amygdalar nuclei50.827718734741245.7515621185303
319504STRStriatum22.492895126342821.1207494735718
319504STRdStriatum dorsal region17.955910682678218.2946367263794
319504STRvStriatum ventral region28.18400669097921.6167001724243
319504THThalamus23.984370231628423.1708860397339
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4897GO:0001764NASProcessneuron migration
4897GO:0005515NASFunctionprotein binding
4897GO:0005887NASComponentintegral to plasma membrane
4897GO:0007413NASProcessaxonal fasciculation
4897GO:0007416TASProcesssynaptogenesis
4897GO:0007417NASProcesscentral nervous system development
4897GO:0009897NASComponentexternal side of plasma membrane
4897GO:0016020IEAComponentmembrane
4897GO:0016337NASProcesscell-cell adhesion
4897GO:0030506IDAFunctionankyrin binding
4897GO:0030516NASProcessregulation of axon extension
4897GO:0043005NASComponentneuron projection
4897GO:0045162IDAProcessclustering of voltage-gated sodium channels
4897GO:0045666NASProcesspositive regulation of neuron differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-23114NP_001005388.1neurofascin isoform 1HPRD12372
NP_005001.25787-Receptor type protein tyrosine phosphatase betaHPRD07207
NP_005001.26900NP_005067.1contactin 2 precursorHPRD07207
NP_005001.26900NP_005067.1contactin 2 precursorHPRD01826
NP_005001.2260425NP_066016.1membrane-associated guanylate kinase-related 3 isoform 1HPRD11290
NP_005001.223499NP_149033.2microfilament and actin filament cross-linker protein isoform bHPRD09750
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4897IPR003962FnIII_subdFibronectin, type III subdomain
4897IPR003961FN_IIIFibronectin, type III
4897IPR013098I-setImmunoglobulin I-set
4897IPR007110Ig-likeImmunoglobulin-like
4897IPR003006Ig_MHCImmunoglobulin/major histocompatibility complex
4897IPR013151ImmunoglobulinImmunoglobulin
4897IPR013106V-setImmunoglobulin V-set
4897IPR009134VEGFRVascular endothelial growth factor receptor, VEGFR
4897NRCAM_HUMANQ92823IPR003962FnIII_subdFibronectin, type III subdomain
4897NRCAM_HUMANQ92823IPR003961FN_IIIFibronectin, type III
4897NRCAM_HUMANQ92823IPR013098I-setImmunoglobulin I-set
4897NRCAM_HUMANQ92823IPR007110Ig-likeImmunoglobulin-like
4897NRCAM_HUMANQ92823IPR003006Ig_MHCImmunoglobulin/major histocompatibility complex
4897NRCAM_HUMANQ92823IPR013151ImmunoglobulinImmunoglobulin
4897NRCAM_HUMANQ92823IPR013106V-setImmunoglobulin V-set
4897NRCAM_HUMANQ92823IPR009134VEGFRVascular endothelial growth factor receptor, VEGFR

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