Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:4974
Official Symbol:OMG
Other Aliases:OMGP
See related:HGNC:8135|MIM:164345|HPRD:01257
Chromosome:17
Location:17q11.2
Gene Description:oligodendrocyte myelin glycoprotein
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0822
ORGANISM:human
Entrez Gene ID:4974
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-2.7 :: -1.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18377CBCerebellum68.3056488037109100.0
18377CTXCerebral cortex100.0100.0
18377HIPHippocampal region96.48054122924898.2457847595215
18377HPFHippocampal formation100.0100.0
18377HYHypothalamus99.823547363281286.9256324768066
18377LSXLateral septal complex88.617511749267673.1596145629883
18377MBMidbrain100.093.1217803955078
18377MYMedulla100.0100.0
18377OLFOlfactory bulb100.0100.0
18377PPons100.0100.0
18377PALPallidum90.96319198608485.8539352416992
18377RHPRetrohippocampal region100.0100.0
18377sAMYStriatum-like amygdalar nuclei100.094.4131088256836
18377STRStriatum74.22183036804255.1193313598633
18377STRdStriatum dorsal region68.745594024658247.0313282012939
18377STRvStriatum ventral region68.202306747436546.8884572982788
18377THThalamus83.076702117919969.9290447235107
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
4974GO:0005515IEAFunctionprotein binding
4974GO:0005624NRComponentmembrane fraction
4974GO:0005887NRComponentintegral to plasma membrane
4974GO:0007155IEAProcesscell adhesion
4974GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002535.2--Nogo 66 receptorHPRD01257
NP_002535.3146760NP_848663.1reticulon 4 receptor-like 1HPRD11523
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
4974OMGP_HUMANP23515IPR000276GPCR_RhodpsnRhodopsin-like GPCR superfamily
4974OMGP_HUMANP23515IPR001611LRRLeucine-rich repeat
4974OMGP_HUMANP23515IPR000372LRR_cys_NLeucine-rich repeat, cysteine-rich flanking region, N-terminal
4974OMGP_HUMANP23515IPR003591LRR_typLeucine-rich repeat, typical subtype

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