Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5037
Official Symbol:PEBP1
Other Aliases:HCNP|PBP|PEBP|RKIP
See related:HGNC:8630|MIM:604591|HPRD:06850
Chromosome:12
Location:12q24.23
Gene Description:phosphatidylethanolamine binding protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0423
ORGANISM:human
Entrez Gene ID:5037
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29542
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
76400CBCerebellum1.191473126411441.57620489597321
23980CBCerebellum27.3216323852539100.0
76400CTXCerebral cortex0.8266375064849851.07817029953003
23980CTXCerebral cortex100.0100.0
76400HIPHippocampal region1.08703958988191.8615528345108
23980HIPHippocampal region100.0100.0
76400HPFHippocampal formation0.9484776258468631.35072636604309
23980HPFHippocampal formation100.0100.0
76400HYHypothalamus0.299963831901550.268646240234375
23980HYHypothalamus56.824851989746159.540412902832
76400LSXLateral septal complex0.9915127754211431.18443870544434
23980LSXLateral septal complex70.918357849121170.5823287963867
76400MBMidbrain0.7563495635986331.13533818721771
23980MBMidbrain65.702110290527377.8384475708008
76400MYMedulla1.878432869911191.85959780216217
23980MYMedulla74.6476745605469100.0
76400OLFOlfactory bulb1.06427633762362.67518877983093
23980OLFOlfactory bulb81.196380615234497.0275497436523
76400PPons0.5116477608680730.508014440536499
23980PPons66.450874328613393.2608108520508
76400PALPallidum0.08693498373031620.091919057071209
23980PALPallidum60.587375640869177.6821594238281
76400RHPRetrohippocampal region0.7333308458328250.668657124042511
23980RHPRetrohippocampal region100.0100.0
76400sAMYStriatum-like amygdalar nuclei0.7963545918464660.724132001399994
23980sAMYStriatum-like amygdalar nuclei72.125518798828173.1581497192383
76400STRStriatum0.8378669023513790.983045876026154
23980STRStriatum77.339935302734471.0847625732422
76400STRdStriatum dorsal region0.9952352046966551.26194703578949
23980STRdStriatum dorsal region80.138870239257873.3026351928711
76400STRvStriatum ventral region0.1563094705343250.14685270190239
23980STRvStriatum ventral region77.631851196289167.0396957397461
76400THThalamus1.027041792869571.38739621639252
23980THThalamus81.529632568359498.5984802246094
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5037GO:0000166IEAFunctionnucleotide binding
5037GO:0004867IEAFunctionserine-type endopeptidase inhibitor activity
5037GO:0005524IEAFunctionATP binding
5037GO:0008289IEAFunctionlipid binding
5037GO:0008429TASFunctionphosphatidylethanolamine binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-5894NP_002871.1v-raf-1 murine leukemia viral oncogene homolog 1HPRD01265
NP_002558.15894-RAF1HPRD06850
NP_002558.15037NP_002558.1prostatic binding proteinHPRD06850
NP_002558.15578NP_002728.1protein kinase C, alphaBIND54432
NP_002558.15594NP_002736.2mitogen-activated protein kinase 1HPRD06850
NP_002558.15604NP_002746.1mitogen-activated protein kinase kinase 1HPRD06850
NP_002558.15894NP_002871.1v-raf-1 murine leukemia viral oncogene homolog 1BIND54431
NP_002558.15580NP_006245.2protein kinase C, deltaBIND54433
NP_002558.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
NP_002558.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD06850
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5037PEBP_HUMANP30086IPR008914PEBPPEBP
5037PEBP_HUMANP30086IPR001858PE_bdPhosphatidylethanolamine-binding protein

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