Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5090
Official Symbol:PBX3
Other Aliases:-
See related:HGNC:8634|MIM:176312|HPRD:15938
Chromosome:9
Location:9q33-q34
Gene Description:pre-B-cell leukemia transcription factor 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0231
ORGANISM:human
Entrez Gene ID:5090
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18516
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18516CBCerebellum11.845455169677712.2862491607666
18516CTXCerebral cortex7.920413494110114.10183620452881
18516HIPHippocampal region3.297198295593262.75103092193604
18516HPFHippocampal formation8.284777641296394.60853719711304
18516HYHypothalamus31.296445846557622.841552734375
18516LSXLateral septal complex35.610130310058619.9732131958008
18516MBMidbrain38.811828613281229.3932628631592
18516MYMedulla27.914854049682621.9308128356934
18516OLFOlfactory bulb59.817043304443478.4445648193359
18516PPons46.015026092529331.2740039825439
18516PALPallidum36.6293945312529.0169658660889
18516RHPRetrohippocampal region14.37831306457526.33875417709351
18516sAMYStriatum-like amygdalar nuclei82.808601379394551.9944114685059
18516STRStriatum67.946617126464836.9532928466797
18516STRdStriatum dorsal region61.972393035888731.7363262176514
18516STRvStriatum ventral region87.186912536621146.8884696960449
18516THThalamus9.266761779785166.68120241165161
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5090GO:0003700IEAFunctiontranscription factor activity
5090GO:0005515ISSFunctionprotein binding
5090GO:0005634IEAComponentnucleus
5090GO:0005634ISSComponentnucleus
5090GO:0006355IEAProcessregulation of transcription, DNA-dependent
5090GO:0007387TASProcessanterior compartment specification
5090GO:0007388TASProcessposterior compartment specification
5090GO:0009790ISSProcessembryonic development
5090GO:0030902ISSProcesshindbrain development
5090GO:0043565IEAFunctionsequence-specific DNA binding
5090GO:0045898ISSProcessregulation of transcriptional preinitiation complex formation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5090PBX3_HUMANP40426IPR001356HomeoboxHomeobox
5090PBX3_HUMANP40426IPR000047HTH_lambrepressrHelix-turn-helix motif, lambda-like repressor
5090PBX3_HUMANP40426IPR005542PBXPBX

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