Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:51195
Official Symbol:RAPGEFL1
Other Aliases:Link-GEFII|MGC134798|MGC134799
See related:HGNC:17428|HPRD:17954
Chromosome:17
Location:17q21.1-q21.2
Gene Description:Rap guanine nucleotide exchange factor (GEF)-like 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0930
ORGANISM:human
Entrez Gene ID:51195
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.5 :: 1.7
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
268480CBCerebellum100.0100.0
268480CTXCerebral cortex100.0100.0
268480HIPHippocampal region100.0100.0
268480HPFHippocampal formation100.0100.0
268480HYHypothalamus100.0100.0
268480LSXLateral septal complex100.0100.0
268480MBMidbrain100.0100.0
268480MYMedulla92.390830993652398.9480285644531
268480OLFOlfactory bulb100.0100.0
268480PPons83.005706787109483.0576629638672
268480PALPallidum100.0100.0
268480RHPRetrohippocampal region100.0100.0
268480sAMYStriatum-like amygdalar nuclei100.0100.0
268480STRStriatum100.0100.0
268480STRdStriatum dorsal region100.0100.0
268480STRvStriatum ventral region100.0100.0
268480THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
51195IPR000159RARA
51195IPR001895RasGRF_CDC25Guanine-nucleotide dissociation stimulator CDC25

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