Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:51268
Official Symbol:PIPOX
Other Aliases:LPIPOX
See related:HGNC:17804|HPRD:17853
Chromosome:17
Location:17q11.2
Gene Description:pipecolic acid oxidase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0263
ORGANISM:human
Entrez Gene ID:51268
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.51
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
19193CBCerebellum8.253036499023449.04629898071289
19193CTXCerebral cortex6.975476741790774.45421600341797
19193HIPHippocampal region7.534984588623058.10670375823975
19193HPFHippocampal formation10.817648887634310.2614393234253
19193HYHypothalamus5.97974777221684.64667844772339
19193LSXLateral septal complex6.678313732147225.24547100067139
19193MBMidbrain3.618364572525023.13511776924133
19193MYMedulla11.852053642272913.9558124542236
19193OLFOlfactory bulb13.538088798522910.4280052185059
19193PPons10.654516220092811.6087465286255
19193PALPallidum6.278193950653084.44863128662109
19193RHPRetrohippocampal region18.957027435302714.9669046401978
19193sAMYStriatum-like amygdalar nuclei6.666052341461184.48433208465576
19193STRStriatum8.938088417053225.90758466720581
19193STRdStriatum dorsal region10.25885009765626.34008598327637
19193STRvStriatum ventral region7.526208877563486.50345277786255
19193THThalamus3.552056550979612.49511408805847
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
51268GO:0005777TASComponentperoxisome
51268GO:0006118IEAProcesselectron transport
51268GO:0008115IEAFunctionsarcosine oxidase activity
51268GO:0016491IEAFunctionoxidoreductase activity
51268GO:0046653IEAProcesstetrahydrofolate metabolism
51268GO:0050031IEAFunctionL-pipecolate oxidase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
51268SOX_HUMANQ9P0Z9IPR006076Fad_oxredFAD dependent oxidoreductase

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