Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:51330
Official Symbol:TNFRSF12A
Other Aliases:CD266|FN14|TWEAKR
See related:HGNC:18152|MIM:605914|HPRD:05801
Chromosome:16
Location:16p13.3
Gene Description:tumor necrosis factor receptor superfamily, member 12A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0935
ORGANISM:human
Entrez Gene ID:51330
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.8 :: 1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
27279CBCerebellum25.006852626800518.11354637146
27279CTXCerebral cortex29.20923757553119.6775367259979
27279HIPHippocampal region31.44684362411518.0571888685226
27279HPFHippocampal formation38.770312309265125.4830358028412
27279HYHypothalamus38.854968190193224.1241897344589
27279LSXLateral septal complex8.726231455802924.33926719427109
27279MBMidbrain22.548637032508915.6664924025536
27279MYMedulla50.194332122802745.1577851772308
27279OLFOlfactory bulb43.723218917846728.3324120044708
27279PPons42.337028026580837.4774205684662
27279PALPallidum24.760068774223317.6352759599686
27279RHPRetrohippocampal region53.018958091735836.7989249229431
27279sAMYStriatum-like amygdalar nuclei47.297392785549227.9534641206264
27279STRStriatum13.97946441173558.1564148068428
27279STRdStriatum dorsal region4.923959851264952.94825267791748
27279STRvStriatum ventral region35.340569972991918.8987412452698
27279THThalamus14.70908153057110.1477437615395
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
51330GO:0001525IEAProcessangiogenesis
51330GO:0004872IEAFunctionreceptor activity
51330GO:0005515IEAFunctionprotein binding
51330GO:0006915IEAProcessapoptosis
51330GO:0006928TASProcesscell motility
51330GO:0007155IEAProcesscell adhesion
51330GO:0016020IEAComponentmembrane
51330GO:0016021IEAComponentintegral to membrane
51330GO:0030154IEAProcesscell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
51330TNR12_HUMANQ9NP84

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