Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:51465
Official Symbol:UBE2J1
Other Aliases:CGI-76|HSPC153|HSPC205|HSU93243|MGC12555|NCUBE1|Ubc6p
See related:HGNC:17598|HPRD:15599
Chromosome:6
Location:6q15
Gene Description:ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0205
ORGANISM:human
Entrez Gene ID:51465
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Upregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
56228CBCerebellum0.00.0
56228CTXCerebral cortex0.00.0
56228HIPHippocampal region0.00.0
56228HPFHippocampal formation0.00.0
56228HYHypothalamus0.00.0
56228LSXLateral septal complex0.00.0
56228MBMidbrain0.00.0
56228MYMedulla0.00.0
56228OLFOlfactory bulb0.00.0
56228PPons0.00.0
56228PALPallidum0.00.0
56228RHPRetrohippocampal region0.00.0
56228sAMYStriatum-like amygdalar nuclei0.00.0
56228STRStriatum0.00.0
56228STRdStriatum dorsal region0.00.0
56228STRvStriatum ventral region0.00.0
56228THThalamus0.00.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
51465GO:0004842IEAFunctionubiquitin-protein ligase activity
51465GO:0005783IEAComponentendoplasmic reticulum
51465GO:0006512IEAProcessubiquitin cycle
51465GO:0016020IEAComponentmembrane
51465GO:0016021IEAComponentintegral to membrane
51465GO:0016874IEAFunctionligase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
51465UB2J1_HUMANQ9Y385IPR000608UBQ-conjugat_E2Ubiquitin-conjugating enzyme, E2

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