Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:518
Official Symbol:ATP5G3
Other Aliases:MGC125738|P3
See related:HGNC:843|MIM:602736|HPRD:04112
Chromosome:2
Location:2q31.1
Gene Description:ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0102
ORGANISM:human
Entrez Gene ID:518
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:0.66 :: 1.39 :: 2.28 :: 1.46 :: -1.64 :: -1.52 :: -1.05
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
228033CBCerebellum47.9012908935547100.0
228033CTXCerebral cortex100.0100.0
228033HIPHippocampal region100.0100.0
228033HPFHippocampal formation100.0100.0
228033HYHypothalamus88.8339309692383100.0
228033LSXLateral septal complex100.0100.0
228033MBMidbrain100.0100.0
228033MYMedulla95.4302291870117100.0
228033OLFOlfactory bulb94.3205032348633100.0
228033PPons94.6184539794922100.0
228033PALPallidum90.5116806030273100.0
228033RHPRetrohippocampal region100.0100.0
228033sAMYStriatum-like amygdalar nuclei90.7579574584961100.0
228033STRStriatum100.0100.0
228033STRdStriatum dorsal region100.0100.0
228033STRvStriatum ventral region90.819358825683692.4127426147461
228033THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
518GO:0005215NASFunctiontransporter activity
518GO:0005515IPIFunctionprotein binding
518GO:0005624NRComponentmembrane fraction
518GO:0005739IEAComponentmitochondrion
518GO:0005753TASComponentproton-transporting ATP synthase complex (sensu Eukaryota)
518GO:0006091NRProcessgeneration of precursor metabolites and energy
518GO:0006811IEAProcession transport
518GO:0008289IEAFunctionlipid binding
518GO:0015986IEAProcessATP synthesis coupled proton transport
518GO:0015992IEAProcessproton transport
518GO:0016020IEAComponentmembrane
518GO:0016469IEAComponentproton-transporting two-sector ATPase complex
518GO:0045263IEAComponentproton-transporting ATP synthase complex, coupling factor F(o)
518GO:0046933IEAFunctionhydrogen-transporting ATP synthase activity, rotational mechanism
518GO:0046961IEAFunctionhydrogen-transporting ATPase activity, rotational mechanism
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001680.17920NP_066983.1HLA-B associated transcript 5HPRD15929
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
518AT5G3_HUMANP48201IPR002379ATPase_F0/V0_cATPase, F0/V0 complex, subunit C
518AT5G3_HUMANP48201IPR000454ATPase_F0_cATPase, F0 complex, subunit C

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