Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5187
Official Symbol:PER1
Other Aliases:MGC88021|PER|RIGUI|hPER
See related:HGNC:8845|MIM:602260|HPRD:03774
Chromosome:17
Location:17p13.1-17p12
Gene Description:period homolog 1 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0222
ORGANISM:human
Entrez Gene ID:5187
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18626
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18626CBCerebellum82.462368011474672.7800540924072
18626CTXCerebral cortex100.087.0813941955566
18626HIPHippocampal region73.294616699218864.7770252227783
18626HPFHippocampal formation83.004962921142671.7377967834473
18626HYHypothalamus48.93556785583533.5836610794067
18626LSXLateral septal complex70.941677093505962.0457038879395
18626MBMidbrain45.363108634948733.3037519454956
18626MYMedulla41.667020797729532.1838541030884
18626OLFOlfactory bulb100.087.7981605529785
18626PPons39.902275085449231.5669565200806
18626PALPallidum40.704229831695632.2131171226501
18626RHPRetrohippocampal region84.108249664306672.6158771514893
18626sAMYStriatum-like amygdalar nuclei62.373488426208545.674241065979
18626STRStriatum87.203872680664174.5839900970459
18626STRdStriatum dorsal region90.014560699462977.2534084320068
18626STRvStriatum ventral region100.081.1017799377441
18626THThalamus80.878747940063569.9995574951172
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5187GO:0003676IEAFunctionnucleic acid binding
5187GO:0004871IEAFunctionsignal transducer activity
5187GO:0005515ISSFunctionprotein binding
5187GO:0005634IEAComponentnucleus
5187GO:0006350IEAProcesstranscription
5187GO:0006355IEAProcessregulation of transcription, DNA-dependent
5187GO:0007165IEAProcesssignal transduction
5187GO:0009649TASProcessentrainment of circadian clock
5187GO:0016481ISSProcessnegative regulation of transcription
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8864NP_073728.1period 2 isoform 1HPRD04575
NP_002607.1--PER3HPRD03774
NP_002607.1--PIPSHPRD03774
NP_002607.1--Cry1HPRD03774
NP_002607.18864-Period circadian protein 2HPRD03774
NP_002607.18914NP_003911.1timeless homologHPRD03774
NP_002607.18914NP_003911.1timeless homologHPRD04864
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5187PER1_HUMANO15534IPR003980H3_rcptHistamine H3 receptor
5187PER1_HUMANO15534IPR000014PASPAS
5187PER1_HUMANO15534IPR013655PAS_3PAS fold-3
5187PER1_HUMANO15534IPR000694PRO_richProline-rich region

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