Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5199
Official Symbol:CFP
Other Aliases:BFD|PFC|PFD|PROPERDIN
See related:HGNC:8864|MIM:300383|HPRD:02308
Chromosome:X
Location:Xp11.3-p11.23
Gene Description:complement factor properdin
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0355
ORGANISM:human
Entrez Gene ID:5199
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.67
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18636CBCerebellum10.138283729553211.0529737472534
18636CTXCerebral cortex19.317844390869112.079119682312
18636HIPHippocampal region23.33188056945822.6820125579834
18636HPFHippocampal formation19.968080520629917.249698638916
18636HYHypothalamus1.436068534851071.41978991031647
18636LSXLateral septal complex3.152987003326422.06522989273071
18636MBMidbrain7.9422206878662110.151385307312
18636MYMedulla4.766322135925293.99218034744263
18636OLFOlfactory bulb17.796277999877912.2058963775635
18636PPons3.734887361526493.32506656646729
18636PALPallidum1.605719447135931.35752236843109
18636RHPRetrohippocampal region14.23457145690929.68190956115723
18636sAMYStriatum-like amygdalar nuclei2.342618465423581.55466771125793
18636STRStriatum3.490047693252562.3537015914917
18636STRdStriatum dorsal region3.913600683212282.7434983253479
18636STRvStriatum ventral region3.245001792907711.96553063392639
18636THThalamus6.391173839569096.05776834487915
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5199GO:0005615TASComponentextracellular space
5199GO:0006957IEAProcesscomplement activation, alternative pathway
5199GO:0042742TASProcessdefense response to bacteria
5199GO:0045087IEAProcessinnate immune response
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002612.1--C3b2-IgGHPRD02308
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5199PROP_HUMANP27918IPR000884TSP1Thrombospondin, type I
5199PROP_HUMANP27918IPR008085TSP_1Thrombospondin, subtype 1

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