Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5283
Official Symbol:PIGH
Other Aliases:GPI-H
See related:HGNC:8964|MIM:600154|HPRD:02540
Chromosome:14
Location:14q11-q24
Gene Description:phosphatidylinositol glycan, class H
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0210
ORGANISM:human
Entrez Gene ID:5283
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11093800
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ADMINISTRATION
Addiction Brain Area:SH-SY5Y neuroblastoma cells
Drug Effects:Downregulated
Fold Change:At least 2-folds difference
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
110417CBCerebellum0.9518339633941652.34546875953674
110417CTXCerebral cortex1.077932715415951.5060750246048
110417HIPHippocampal region1.290118575096132.53781247138977
110417HPFHippocampal formation1.002628207206731.70433437824249
110417HYHypothalamus0.179674640297890.213074952363968
110417LSXLateral septal complex0.1960268169641490.186646148562431
110417MBMidbrain0.4597950279712680.762732267379761
110417MYMedulla0.6577877998352050.675471127033234
110417OLFOlfactory bulb0.3878099322319030.780028879642487
110417PPons0.9139045476913451.63389551639557
110417PALPallidum0.1833192557096480.216809213161469
110417RHPRetrohippocampal region0.420302569866180.433615565299988
110417sAMYStriatum-like amygdalar nuclei0.09180277585983280.0753238946199417
110417STRStriatum0.1364441365003590.1854038387537
110417STRdStriatum dorsal region0.1380821466445920.247780233621597
110417STRvStriatum ventral region0.1125008836388590.0799111127853394
110417THThalamus0.3569564223289490.36873260140419
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5283GO:0005783TASComponentendoplasmic reticulum
5283GO:0006464TASProcessprotein modification
5283GO:0006506TASProcessGPI anchor biosynthesis
5283GO:0016757IEAFunctiontransferase activity, transferring glycosyl groups
5283GO:0017176IEAFunctionphosphatidylinositol N-acetylglucosaminyltransferase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004560.19091NP_683721.1phosphatidylinositol glycan, class Q isoform 1HPRD02540
NP_004560.19091NP_683721.1phosphatidylinositol glycan, class Q isoform 1HPRD09307
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5283PIGH_HUMANQ14442

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