Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5297
Official Symbol:PIK4CA
Other Aliases:FLJ16556|PI4K-ALPHA|pi4K230
See related:HGNC:8983|MIM:600286|HPRD:08972
Chromosome:22
Location:22q11.21
Gene Description:phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0531
ORGANISM:human
Entrez Gene ID:5297
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:64161
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5297GO:0004428IEAFunctioninositol or phosphatidylinositol kinase activity
5297GO:0004430TASFunction1-phosphatidylinositol 4-kinase activity
5297GO:0005515IPIFunctionprotein binding
5297GO:0005798TASComponentGolgi-associated vesicle
5297GO:0006661TASProcessphosphatidylinositol biosynthesis
5297GO:0007165NASProcesssignal transduction
5297GO:0007268TASProcesssynaptic transmission
5297GO:0016740IEAFunctiontransferase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_477352.1-CAB46677.1polyproteinBIND195942
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5297PI4KA_HUMANP42356IPR000403PI3/4_kinase_catPhosphatidylinositol 3- and 4-kinase, catalytic
5297PI4KA_HUMANP42356IPR001263PI3KaPhosphoinositide 3-kinase accessory region PIK
5297PI4KA_HUMANP42356IPR004827TF_bZIPBasic-leucine zipper (bZIP) transcription factor

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