Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5396
Official Symbol:PRRX1
Other Aliases:PHOX1|PMX1|PRX1
See related:HGNC:9142|MIM:167420|HPRD:01337
Chromosome:1
Location:1q24
Gene Description:paired related homeobox 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0570
ORGANISM:human
Entrez Gene ID:5396
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:266813
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5396GO:0003700IEAFunctiontranscription factor activity
5396GO:0003713TASFunctiontranscription coactivator activity
5396GO:0005634IEAComponentnucleus
5396GO:0006355IEAProcessregulation of transcription, DNA-dependent
5396GO:0007275IEAProcessdevelopment
5396GO:0043565IEAFunctionsequence-specific DNA binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-6722NP_003122.1serum response factor (c-fos serum response element-binding transcription factor)HPRD02788
NP_008833.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5396IPR001356HomeoboxHomeobox
5396IPR000047HTH_lambrepressrHelix-turn-helix motif, lambda-like repressor
5396IPR007104Paired_homeoPaired-like homeobox
5396IPR000327POUPOU
5396PRRX1_HUMANP54821IPR001356HomeoboxHomeobox
5396PRRX1_HUMANP54821IPR003654Homeo_OARPaired-like homeodomain protein, OAR
5396PRRX1_HUMANP54821IPR000047HTH_lambrepressrHelix-turn-helix motif, lambda-like repressor
5396PRRX1_HUMANP54821IPR007104Paired_homeoPaired-like homeobox
5396PRRX1_HUMANP54821IPR000327POUPOU

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