Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5496
Official Symbol:PPM1G
Other Aliases:MGC1675|MGC2870|PP2CG|PP2CGAMMA|PPP2CG
See related:HGNC:9278|MIM:605119|HPRD:09237
Chromosome:2
Location:2p23.3
Gene Description:protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0336
ORGANISM:human
Entrez Gene ID:5496
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:14208
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14208CBCerebellum44.319247245788639.0827264785767
14208CTXCerebral cortex80.623165130615271.1115608215332
14208HIPHippocampal region80.457654953002977.860933303833
14208HPFHippocampal formation81.511407852172975.6054363250732
14208HYHypothalamus72.977287292480563.3415365219116
14208LSXLateral septal complex68.686439514160247.8776350021362
14208MBMidbrain67.17136573791555.2294540405273
14208MYMedulla58.846400260925360.5149440765381
14208OLFOlfactory bulb89.754188537597775.3776245117188
14208PPons63.238358497619659.4385395050049
14208PALPallidum64.343456268310548.7127923965454
14208RHPRetrohippocampal region83.514648437572.4909324645996
14208sAMYStriatum-like amygdalar nuclei74.988315582275464.6318531036377
14208STRStriatum60.809741020202635.4209427833557
14208STRdStriatum dorsal region52.27698516845727.7828574180603
14208STRvStriatum ventral region69.144723892211939.1311931610107
14208THThalamus69.804716110229563.9902238845825
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5496GO:0000287IEAFunctionmagnesium ion binding
5496GO:0005634TASComponentnucleus
5496GO:0006470TASProcessprotein amino acid dephosphorylation
5496GO:0007050TASProcesscell cycle arrest
5496GO:0008287IEAComponentprotein serine/threonine phosphatase complex
5496GO:0015071TASFunctionprotein phosphatase type 2C activity
5496GO:0016787IEAFunctionhydrolase activity
5496GO:0030145IEAFunctionmanganese ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5496PP2CG_HUMANO15355IPR000222PP2CProtein phosphatase 2C
5496PP2CG_HUMANO15355IPR001932PP2C-likeProtein phosphatase 2C-like

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