Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5500
Official Symbol:PPP1CB
Other Aliases:MGC3672|PP-1B|PPP1CD
See related:HGNC:9282|MIM:600590|HPRD:11792
Chromosome:2
Location:2p23
Gene Description:protein phosphatase 1, catalytic subunit, beta isoform
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0618
ORGANISM:human
Entrez Gene ID:5500
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25594
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5500GO:0004721IEAFunctionphosphoprotein phosphatase activity
5500GO:0005506IEAFunctioniron ion binding
5500GO:0005975IEAProcesscarbohydrate metabolism
5500GO:0005977IEAProcessglycogen metabolism
5500GO:0007049IEAProcesscell cycle
5500GO:0016787IEAFunctionhydrolase activity
5500GO:0030145IEAFunctionmanganese ion binding
5500GO:0046872IEAFunctionmetal ion binding
5500GO:0051301IEAProcesscell division
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-51729-WW domain binding protein 11HPRD18293
-5747NP_005598.3PTK2 protein tyrosine kinase 2 isoform bHPRD02859
NP_002700.15747-FAKHPRD11792
NP_002700.151729-WW domain binding protein 11HPRD11792
NP_002700.18517NP_003630.1inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gammaHPRD11792
NP_002700.154776NP_060077.1protein phosphatase 1, regulatory subunit 12CHPRD11452
NP_002700.154776NP_060077.1protein phosphatase 1, regulatory subunit 12CHPRD11792
NP_002700.1155871NP_057853.1Tat--
NP_002700.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5500PP1B_HUMANP62140IPR004843M-pesteraseMetallophosphoesterase
5500PP1B_HUMANP62140IPR013622Metallophos_CCalcineurin-like phosphoesterase C-terminal
5500PP1B_HUMANP62140IPR006186T_phtase_apaHSerine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase

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