Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5502
Official Symbol:PPP1R1A
Other Aliases:-
See related:HGNC:9286|HPRD:17893
Chromosome:12
Location:12q13.2
Gene Description:protein phosphatase 1, regulatory (inhibitor) subunit 1A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0081
ORGANISM:human
Entrez Gene ID:5502
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:58200
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
58200CBCerebellum9.835019111633310.5007762908936
58200CTXCerebral cortex100.082.0597915649414
58200HIPHippocampal region93.2195587158203100.0
58200HPFHippocampal formation87.15808868408295.8224716186523
58200HYHypothalamus26.566323280334512.6074676513672
58200LSXLateral septal complex34.480857849121115.6092681884766
58200MBMidbrain28.043554306030316.2339482307434
58200MYMedulla22.569932937622116.4529376029968
58200OLFOlfactory bulb100.086.7912559509277
58200PPons24.965970039367717.285626411438
58200PALPallidum31.33956050872816.677234172821
58200RHPRetrohippocampal region79.631088256835959.8555736541748
58200sAMYStriatum-like amygdalar nuclei43.016616821289118.4352588653564
58200STRStriatum99.452201843261756.1431102752686
58200STRdStriatum dorsal region100.063.3624744415283
58200STRvStriatum ventral region100.066.5058097839355
58200THThalamus28.215036392211915.307701587677
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5502GO:0004865TASFunctiontype 1 serine/threonine specific protein phosphatase inhibitor activity
5502GO:0005975IEAProcesscarbohydrate metabolism
5502GO:0005977IEAProcessglycogen metabolism
5502GO:0007165IEAProcesssignal transduction
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5502IPP1_HUMANQ13522IPR008466DARPP-32Protein phosphatase inhibitor, 1DARPP-32
5502IPP1_HUMANQ13522IPR002211LymphspecificLymphocyte-specific protein

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