Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5527
Official Symbol:PPP2R5C
Other Aliases:B56G|MGC23064
See related:HGNC:9311|MIM:601645|HPRD:03385
Chromosome:14
Location:14q32
Gene Description:protein phosphatase 2, regulatory subunit B (B56), gamma isoform
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0421
ORGANISM:human
Entrez Gene ID:5527
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:1 :: 1.2 :: -1 :: -1.3 :: -1.6
KARG Evidence 2
KARG ID:EVIM0489
ORGANISM:human
Entrez Gene ID:5527
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.5 :: -1.5 :: -1.6 :: -1.5 :: -1
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5527GO:0000159IEAComponentprotein phosphatase type 2A complex
5527GO:0000159NASComponentprotein phosphatase type 2A complex
5527GO:0005634IDAComponentnucleus
5527GO:0007165IEAProcesssignal transduction
5527GO:0007165NASProcesssignal transduction
5527GO:0008233IDAFunctionpeptidase activity
5527GO:0008601IEAFunctionprotein phosphatase type 2A regulator activity
5527GO:0008601NASFunctionprotein phosphatase type 2A regulator activity
5527GO:0016021IDAComponentintegral to membrane
5527GO:0016485IDAProcessprotein processing
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_002710.1155030NP_579881.1nucleocapsid--
NP_002710.2--PP2A catalytic subunit CHPRD03385
NP_002710.2155807NP_057852.2Vpr--
NP_002710.2155807NP_057852.2Vpr--
NP_002710.2155807NP_057852.2Vpr--
NP_002710.2155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5527IPR002554B56Protein phosphatase 2A, regulatory B subunit, B56
55272A5G_HUMANQ13362IPR002554B56Protein phosphatase 2A, regulatory B subunit, B56

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