Knowledgebase for Addiction-Related Genes
KARG (Knowledgebase for Addiction Related
>> Gene Entry
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.
Basic Information Gene ID: 5575 Official Symbol: PRKAR1B Other Aliases: PRKAR1 See related: HGNC:9390|MIM:176911|HPRD:01485 Chromosome: 7 Location: 7p22 Gene Description: protein kinase, cAMP-dependent, regulatory, type I, beta Gene type: protein-coding Gene Structure: Genomic Context:
KARG Evidence 1 KARG ID: EVIC0034 ORGANISM: human Entrez Gene ID: 5575 Evidence Type: Mapping from mouse Evidence ID Type: Entrez Gene Evidence ID: 19085 Addiction Drug: Addiction Drug Detail: Addiction Brain Area: Drug Effects: Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density
Gene Ontology Gene ID GO ID Evidence GO Type GO Description 5575 GO:0000166 IEA Function nucleotide binding 5575 GO:0005952 NAS Component cAMP-dependent protein kinase complex 5575 GO:0006468 NAS Process protein amino acid phosphorylation 5575 GO:0007165 IEA Process signal transduction 5575 GO:0008603 NAS Function cAMP-dependent protein kinase regulator activity 5575 GO:0030552 IEA Function cAMP binding
Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 55607 BAA90928.1 unnamed protein product HPRD 16000 NP_002726.1 8165 NP_003479.1 A-kinase anchor protein 1 isoform 1 precursor HPRD 03905 NP_002726.1 155871 NP_057853.1 Tat - - NP_002726.1 155030 NP_579876.2 matrix - - NP_002726.1 155030 NP_579876.2 matrix - -
Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 5575 KAP1_HUMAN P31321 IPR002373 cAMP_kin cAMP-dependent protein kinase 5575 KAP1_HUMAN P31321 IPR000595 cNMP_bd Cyclic nucleotide-binding 5575 KAP1_HUMAN P31321 IPR003117 RIIa cAMP-dependent protein kinase regulator, type II PKA R subunit
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