Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5625
Official Symbol:PRODH
Other Aliases:HSPOX2|PIG6|PRODH1|PRODH2|SCZD4|TP53I6
See related:HGNC:9453|MIM:606810|HPRD:08433
Chromosome:22
Location:22q11.21
Gene Description:proline dehydrogenase (oxidase) 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0860
ORGANISM:human
Entrez Gene ID:5625
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.9
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5625GO:0004657IEAFunctionproline dehydrogenase activity
5625GO:0004657TASFunctionproline dehydrogenase activity
5625GO:0005554NDFunctionmolecular function unknown
5625GO:0005739IEAComponentmitochondrion
5625GO:0006537IEAProcessglutamate biosynthesis
5625GO:0006562IEAProcessproline catabolism
5625GO:0008372NDComponentcellular component unknown
5625GO:0008631NASProcessinduction of apoptosis by oxidative stress
5625GO:0016491IEAFunctionoxidoreductase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5625PROD_HUMANO43272IPR002872Proline_DHProline dehydrogenase

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