Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:56287
Official Symbol:GKN1
Other Aliases:AMP18|BRICD1|CA11|FOV|MGC70354|foveolin
See related:HGNC:23217|MIM:606402|HPRD:16217
Chromosome:2
Location:2p14
Gene Description:gastrokine 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0301
ORGANISM:human
Entrez Gene ID:56287
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.67
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
66283CBCerebellum0.7419386506080631.30644726753235
66283CTXCerebral cortex0.8915911912918091.26906585693359
66283HIPHippocampal region0.7043265700340270.729786157608032
66283HPFHippocampal formation0.6025288105010990.582704246044159
66283HYHypothalamus0.1230167374014850.200474441051483
66283LSXLateral septal complex0.06501103937625890.073863722383976
66283MBMidbrain0.2925131618976590.424058943986893
66283MYMedulla1.737824797630312.23492479324341
66283OLFOlfactory bulb0.693302333354951.5434798002243
66283PPons0.2023683190345760.285783767700195
66283PALPallidum0.4561690688133240.481868475675583
66283RHPRetrohippocampal region0.4459304511547090.394788414239883
66283sAMYStriatum-like amygdalar nuclei0.3786886036396030.379585117101669
66283STRStriatum0.6094298362731930.721502184867859
66283STRdStriatum dorsal region0.8606557846069341.08943212032318
66283STRvStriatum ventral region0.2953456938266750.225339069962502
66283THThalamus0.4190513491630550.479100614786148
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
56287GO:0000074IEAProcessregulation of progression through cell cycle
56287GO:0005554NDFunctionmolecular function unknown
56287GO:0007586NASProcessdigestion
56287GO:0008083IEAFunctiongrowth factor activity
56287GO:0008283IEAProcesscell proliferation
56287GO:0008372NDComponentcellular component unknown
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
56287GKN1_HUMANQ9NS71IPR007084BRICHOSBRICHOS

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