Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:57447
Official Symbol:NDRG2
Other Aliases:DKFZp781G1938|KIAA1248|SYLD
See related:HGNC:14460|MIM:605272|HPRD:17630
Chromosome:14
Location:14q11.2
Gene Description:NDRG family member 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0081
ORGANISM:human
Entrez Gene ID:57447
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.56 :: 0.00 :: -0.46 :: -0.94 :: -0.96 :: -0.68 :: -0.37 :: -0.35 :: -0.05 :: -0.85
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
29811CBCerebellum70.838679631551195.3046188354492
29811CTXCerebral cortex84.675090789794969.6124560038249
29811HIPHippocampal region90.029495239257885.7027130126953
29811HPFHippocampal formation96.067868550618592.4503122965495
29811HYHypothalamus96.582547505696691.2318929036458
29811LSXLateral septal complex62.871633211771652.3942829767863
29811MBMidbrain81.079916636149178.287181854248
29811MYMedulla79.914309183756583.6785888671875
29811OLFOlfactory bulb83.694372812906982.4062004089355
29811PPons84.650357564290486.1484069824219
29811PALPallidum93.773234049479290.7646891276042
29811RHPRetrohippocampal region100.0100.0
29811sAMYStriatum-like amygdalar nuclei98.320259094238388.7134730021159
29811STRStriatum76.283524831136165.7310320536296
29811STRdStriatum dorsal region71.096422831217561.3420130411784
29811STRvStriatum ventral region80.253986358642662.7483666737874
29811THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
57447GO:0005554NDFunctionmolecular function unknown
57447GO:0005829NASComponentcytosol
57447GO:0030154IEAProcesscell differentiation
57447GO:0030154ISSProcesscell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_963293.181532NP_443731.2HCCA2 proteinHPRD17581
NP_963293.181532NP_443731.2HCCA2 proteinHPRD17630
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
57447IPR004142NdrNdr
57447NDRG2_HUMANQ9UN36IPR004142NdrNdr

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