Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5860
Official Symbol:QDPR
Other Aliases:DHPR|FLJ42391|PKU2
See related:HGNC:9752|MIM:261630|HPRD:02025
Chromosome:4
Location:4p15.31
Gene Description:quinoid dihydropteridine reductase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0349
ORGANISM:human
Entrez Gene ID:5860
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:110391
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC0590
ORGANISM:human
Entrez Gene ID:5860
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:64192
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
110391CBCerebellum49.67779159545950.0
110391CTXCerebral cortex50.038.6964645385742
110391HIPHippocampal region42.274009704589843.8375511169434
110391HPFHippocampal formation47.482433319091841.7381706237793
110391HYHypothalamus50.050.0
110391LSXLateral septal complex50.047.8814582824707
110391MBMidbrain50.050.0
110391MYMedulla50.050.0
110391OLFOlfactory bulb50.042.6869926452637
110391PPons50.050.0
110391PALPallidum50.050.0
110391RHPRetrohippocampal region50.038.3506927490234
110391sAMYStriatum-like amygdalar nuclei50.047.9771728515625
110391STRStriatum49.414020538330139.8648223876953
110391STRdStriatum dorsal region49.692508697509842.4387474060059
110391STRvStriatum ventral region39.760662078857427.3165645599365
110391THThalamus50.050.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5860GO:0004155TASFunction6,7-dihydropteridine reductase activity
5860GO:0006520TASProcessamino acid metabolism
5860GO:0006559IEAProcessL-phenylalanine catabolism
5860GO:0006729IEAProcesstetrahydrobiopterin biosynthesis
5860GO:0008152IEAProcessmetabolism
5860GO:0016491IEAFunctionoxidoreductase activity
5860GO:0051066TASProcessdihydrobiopterin metabolism
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5860DHPR_HUMANP09417IPR002347ADH_short_C2Glucose/ribitol dehydrogenase
5860DHPR_HUMANP09417IPR002198SDRShort-chain dehydrogenase/reductase SDR

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