Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5864
Official Symbol:RAB3A
Other Aliases:-
See related:HGNC:9777|MIM:179490|HPRD:01535
Chromosome:19
Location:19p13.2
Gene Description:RAB3A, member RAS oncogene family
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0479
ORGANISM:human
Entrez Gene ID:5864
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25531
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
19339CBCerebellum100.0100.0
19339CTXCerebral cortex100.0100.0
19339HIPHippocampal region100.0100.0
19339HPFHippocampal formation100.0100.0
19339HYHypothalamus100.0100.0
19339LSXLateral septal complex100.0100.0
19339MBMidbrain100.0100.0
19339MYMedulla100.0100.0
19339OLFOlfactory bulb100.0100.0
19339PPons100.0100.0
19339PALPallidum100.0100.0
19339RHPRetrohippocampal region100.0100.0
19339sAMYStriatum-like amygdalar nuclei100.0100.0
19339STRStriatum100.0100.0
19339STRdStriatum dorsal region100.0100.0
19339STRvStriatum ventral region100.0100.0
19339THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5864GO:0000166IEAFunctionnucleotide binding
5864GO:0003924IMPFunctionGTPase activity
5864GO:0005515IPIFunctionprotein binding
5864GO:0005515ISSFunctionprotein binding
5864GO:0005525IEAFunctionGTP binding
5864GO:0006887IEAProcessexocytosis
5864GO:0007264IEAProcesssmall GTPase mediated signal transduction
5864GO:0007269TASProcessneurotransmitter secretion
5864GO:0008021TASComponentsynaptic vesicle
5864GO:0015031IEAProcessprotein transport
5864GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-5876NP_004573.2Rab geranylgeranyltransferase, beta subunitHPRD01532
-9501NP_008918.1rabphilin 3A-like (without C2 domains)HPRD05345
-5866NP_037533.2RAB3A interacting protein (rabin3)-like 1HPRD10181
-9699NP_055492.2regulating synaptic membrane exocytosis 2HPRD09436
-22895NP_055769.2rabphilin 3A homologHPRD15273
-23312NP_056078.1Dmx-like 2HPRD10188
-94121NP_542775.1synaptotagmin-like 4 (granuphilin-a)HPRD06735
-94122NP_620135.1synaptotagmin-like 5HPRD06736
-117177NP_783322.1RAB3A interacting protein isoform alpha 2HPRD10565
NP_002857.1--GRABHPRD01535
NP_002857.1--Slp4-aHPRD01535
NP_002857.1--Rim1HPRD01535
NP_002857.1--Rim2HPRD01535
NP_002857.1--Rabphilin 3AHPRD01535
NP_002857.15876-RAB geranylgeranyltransferase, beta subunitHPRD01535
NP_002857.15877-MSS4HPRD01535
NP_002857.110567-Rab acceptor 1HPRD01535
NP_002857.19501-NOC2HPRD01535
NP_002857.194121-Synaptotagmin like 4HPRD01535
NP_002857.194122-Synaptotagmin like 5HPRD01535
NP_002857.19699-Regulating synaptic membrane exocytosis 2HPRD01535
NP_002857.15877NP_002862.2RAB-interacting factorHPRD04566
NP_002857.18573NP_003679.1calcium/calmodulin-dependent serine protein kinase (MAGUK family)HPRD02164
NP_002857.18573NP_003679.1calcium/calmodulin-dependent serine protein kinase (MAGUK family)HPRD01535
NP_002857.110567NP_006414.1Rab acceptor 1HPRD05375
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5864RAB3A_HUMANP20336IPR006689ARF/SARARF/SAR superfamily
5864RAB3A_HUMANP20336IPR013684Miro-likeMiro-like
5864RAB3A_HUMANP20336IPR013753RasRas
5864RAB3A_HUMANP20336IPR001806Ras_trnsfrmngRas GTPase

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