Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5865
Official Symbol:RAB3B
Other Aliases:-
See related:HGNC:9778|MIM:179510|HPRD:01540
Chromosome:1
Location:1p32-p31
Gene Description:RAB3B, member RAS oncogene family
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0908
ORGANISM:human
Entrez Gene ID:5865
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 2.4 :: -1.5
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
69908CBCerebellum35.191907882690451.1709289550781
69908CTXCerebral cortex52.086299896240253.4276752471924
69908HIPHippocampal region29.494599342346245.8971424102783
69908HPFHippocampal formation49.06150245666564.9691734313965
69908HYHypothalamus32.066769599914632.2486686706543
69908LSXLateral septal complex29.826816558837928.3635272979736
69908MBMidbrain14.151830673217813.8198580741882
69908MYMedulla36.377048492431641.0829696655273
69908OLFOlfactory bulb72.201141357421989.5710906982422
69908PPons21.351803779602126.4587106704712
69908PALPallidum47.744342803955164.8718090057373
69908RHPRetrohippocampal region76.917137145996186.0957221984863
69908sAMYStriatum-like amygdalar nuclei48.353906631469744.7890186309814
69908STRStriatum34.879269599914632.3188219070435
69908STRdStriatum dorsal region29.13249301910427.6377363204956
69908STRvStriatum ventral region45.928548812866238.3160600662231
69908THThalamus18.74573516845716.5697565078735
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5865GO:0000166IEAFunctionnucleotide binding
5865GO:0003924TASFunctionGTPase activity
5865GO:0005525IEAFunctionGTP binding
5865GO:0007264IEAProcesssmall GTPase mediated signal transduction
5865GO:0015031IEAProcessprotein transport
5865GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-9501NP_008918.1rabphilin 3A-like (without C2 domains)HPRD05345
-9699NP_055492.2regulating synaptic membrane exocytosis 2HPRD09436
-22895NP_055769.2rabphilin 3A homologHPRD15273
NP_002858.2--pIgRHPRD01540
NP_002858.29501-NOC2HPRD01540
NP_002858.29699-Regulating synaptic membrane exocytosis 2HPRD01540
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5865RAB3B_HUMANP20337IPR013684Miro-likeMiro-like
5865RAB3B_HUMANP20337IPR013753RasRas
5865RAB3B_HUMANP20337IPR001806Ras_trnsfrmngRas GTPase

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