Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5888
Official Symbol:RAD51
Other Aliases:BRCC5|HRAD51|HsRad51|HsT16930|RAD51A|RECA
See related:HGNC:9817|MIM:179617|HPRD:01557
Chromosome:15
Location:15q15.1
Gene Description:RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0309
ORGANISM:human
Entrez Gene ID:5888
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:1.03
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5888GO:0000166IEAFunctionnucleotide binding
5888GO:0000724ISSProcessdouble-strand break repair via homologous recombination
5888GO:0000724TASProcessdouble-strand break repair via homologous recombination
5888GO:0000795ISSComponentsynaptonemal complex
5888GO:0003684IEAFunctiondamaged DNA binding
5888GO:0003690IDAFunctiondouble-stranded DNA binding
5888GO:0003690ISSFunctiondouble-stranded DNA binding
5888GO:0003697IDAFunctionsingle-stranded DNA binding
5888GO:0005515ISSFunctionprotein binding
5888GO:0005524IEAFunctionATP binding
5888GO:0005634IDAComponentnucleus
5888GO:0005634ISSComponentnucleus
5888GO:0006268IDAProcessDNA unwinding during replication
5888GO:0006268ISSProcessDNA unwinding during replication
5888GO:0006281ISSProcessDNA repair
5888GO:0006312TASProcessmitotic recombination
5888GO:0007126ISSProcessmeiosis
5888GO:0007131ISSProcessmeiotic recombination
5888GO:0008094IEAFunctionDNA-dependent ATPase activity
5888GO:0017111IEAFunctionnucleoside-triphosphatase activity
5888GO:0030528IEAFunctiontranscription regulator activity
5888GO:0042802IPIFunctionidentical protein binding
5888GO:0043142IDAFunctionsingle-stranded DNA-dependent ATPase activity
5888GO:0051106IDAProcesspositive regulation of DNA ligation
5888GO:0051260IPIProcessprotein homooligomerization
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7157NP_000537.2tumor protein p53HPRD01859
-7341NP_003343.1SMT3 suppressor of mif two 3 homolog 1 isoform a precursorHPRD03554
-8438NP_003570.1RAD54-like proteinHPRD04683
-25788NP_036547.1RAD54 homolog BHPRD05049
-283987NP_085133.1hypothetical protein LOC283987HPRD05766
-1491938NP_057864.1p40BIND300752
NP_002866.2--UBE2IHPRD01557
NP_002866.2--Tid1HPRD01557
NP_002866.2--Rad55HPRD01557
NP_002866.2--RPAHPRD01557
NP_002866.2---BIND149251
NP_002866.2---BIND149250
NP_002866.2---BIND149241
NP_002866.27157-p53HPRD01557
NP_002866.27341-SUMO1HPRD01557
NP_002866.2283987-C7ORF28 proteinHPRD01557
NP_002866.225788-RAD54BHPRD01557
NP_002866.28438-RAD54-like proteinHPRD01557
NP_002866.210635AAH16330.1RAD51AP1 proteinHPRD04350
NP_002866.210635AAH16330.1RAD51AP1 proteinHPRD01557
NP_002866.27329NP_003336.1ubiquitin-conjugating enzyme E2IHPRD09045
NP_002866.211144NP_008999.2DMC1 dosage suppressor of mck1 homologHPRD04099
NP_002866.211144NP_008999.2DMC1 dosage suppressor of mck1 homologHPRD01557
NP_002866.256647NP_057651.1BRCA2 and CDKN1A-interacting protein isoform BCCIPalphaHPRD16542
NP_002866.2155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5888IPR000445HhHHelix-hairpin-helix motif
5888IPR013632Rad51_CRad51, C-terminal
5888IPR001553RecA_bacRecA bacterial DNA recombination
5888RAD51_HUMANQ06609IPR000445HhHHelix-hairpin-helix motif
5888RAD51_HUMANQ06609IPR013632Rad51_CRad51, C-terminal
5888RAD51_HUMANQ06609IPR001553RecA_bacRecA bacterial DNA recombination

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.