Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5922
Official Symbol:RASA2
Other Aliases:GAP1M
See related:HGNC:9872|MIM:601589
Chromosome:3
Location:3q22-q23
Gene Description:RAS p21 protein activator 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0619
ORGANISM:human
Entrez Gene ID:5922
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25597
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
114713CBCerebellum10.010046958923311.6981019973755
114713CTXCerebral cortex12.25103187561048.54806709289551
114713HIPHippocampal region6.378697395324715.70317125320435
114713HPFHippocampal formation4.976262569427494.14016389846802
114713HYHypothalamus1.192708969116210.988236963748932
114713LSXLateral septal complex3.301892757415772.4338231086731
114713MBMidbrain4.865913867950445.18478298187256
114713MYMedulla9.020620346069349.42867755889893
114713OLFOlfactory bulb52.196830749511763.9501495361328
114713PPons4.931855201721194.37078666687012
114713PALPallidum1.817331910133361.43653428554535
114713RHPRetrohippocampal region2.481579780578611.85772240161896
114713sAMYStriatum-like amygdalar nuclei0.9503898620605470.66551685333252
114713STRStriatum2.079748868942261.56777811050415
114713STRdStriatum dorsal region1.736652970314031.43331933021545
114713STRvStriatum ventral region3.205680847167971.99846470355988
114713THThalamus4.153944015502933.50400876998901
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5922GO:0005099TASFunctionRas GTPase activator activity
5922GO:0007242IEAProcessintracellular signaling cascade
5922GO:0008270IEAFunctionzinc ion binding
5922GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
BAA11621.1--TaxHPRD03351
NP_006497.21491938NP_057864.1p40BIND300754
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5922RASA2_HUMANQ15283IPR000104Antifreeze_1Antifreeze protein, type I
5922RASA2_HUMANQ15283IPR001562BTKTec/Btk
5922RASA2_HUMANQ15283IPR000008C2C2
5922RASA2_HUMANQ15283IPR001849PHPleckstrin-like
5922RASA2_HUMANQ15283IPR013583PRT_C_plnPhosphoribosyltransferase C-terminal, plant
5922RASA2_HUMANQ15283IPR001936RasGAPRas GTPase-activating protein

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