Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:5998
Official Symbol:RGS3
Other Aliases:C2PA|FLJ20370|FLJ31516|FLJ90496|PDZ-RGS3|RGP3
See related:HGNC:9999|MIM:602189|HPRD:03720
Chromosome:9
Location:9q32
Gene Description:regulator of G-protein signalling 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM1140
ORGANISM:human
Entrez Gene ID:5998
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12716423
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Ventral Tegmental Area
Drug Effects:Upregulated
Fold Change:-
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
5998GO:0000188TASProcessinactivation of MAPK activity
5998GO:0004871IEAFunctionsignal transducer activity
5998GO:0005096TASFunctionGTPase activator activity
5998GO:0005515IEAFunctionprotein binding
5998GO:0005634IEAComponentnucleus
5998GO:0005829TASComponentcytosol
5998GO:0008277TASProcessregulation of G-protein coupled receptor protein signaling pathway
5998GO:0009968IEAProcessnegative regulation of signal transduction
5998GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-7534NP_003397.1tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptideHPRD03183
-7531NP_006752.1tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptideHPRD05457
NP_652759.1--G alpha 11HPRD03720
NP_652759.17531-14-3-3 epsilonHPRD03720
NP_652759.17534-14-3-3 zetaHPRD03720
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
5998IPR000008C2C2
5998IPR001478PDZPDZ/DHR/GLGF
5998IPR000694PRO_richProline-rich region
5998IPR013583PRT_C_plnPhosphoribosyltransferase C-terminal, plant
5998IPR000342RGSRegulator of G protein signalling
5998RGS3_HUMANP49796IPR000008C2C2
5998RGS3_HUMANP49796IPR001478PDZPDZ/DHR/GLGF
5998RGS3_HUMANP49796IPR000694PRO_richProline-rich region
5998RGS3_HUMANP49796IPR013583PRT_C_plnPhosphoribosyltransferase C-terminal, plant
5998RGS3_HUMANP49796IPR000342RGSRegulator of G protein signalling

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.