Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:6157
Official Symbol:RPL27A
Other Aliases:MGC87238
See related:HGNC:10329|MIM:603637|HPRD:04701
Chromosome:11
Location:11p15
Gene Description:ribosomal protein L27a
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0974
ORGANISM:human
Entrez Gene ID:6157
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-2 :: -2.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
26451CBCerebellum44.652565002441462.3503303527832
26451CTXCerebral cortex100.0100.0
26451HIPHippocampal region100.0100.0
26451HPFHippocampal formation100.0100.0
26451HYHypothalamus100.0100.0
26451LSXLateral septal complex100.0100.0
26451MBMidbrain100.0100.0
26451MYMedulla87.1641616821289100.0
26451OLFOlfactory bulb92.549743652343897.8631896972656
26451PPons85.3355178833008100.0
26451PALPallidum90.5214767456055100.0
26451RHPRetrohippocampal region100.0100.0
26451sAMYStriatum-like amygdalar nuclei100.0100.0
26451STRStriatum100.0100.0
26451STRdStriatum dorsal region100.0100.0
26451STRvStriatum ventral region100.0100.0
26451THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
6157GO:0003723TASFunctionRNA binding
6157GO:0003735TASFunctionstructural constituent of ribosome
6157GO:0005840IEAComponentribosome
6157GO:0005842TASComponentcytosolic large ribosomal subunit (sensu Eukaryota)
6157GO:0006412TASProcessprotein biosynthesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
6157RL27A_HUMANP46776IPR001196Ribosomal_L15Ribosomal protein L15

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